Risedronate sodium

Mobile phase A MeCN 10 mM sodium phosphate containing 5 mM 1-ocfyltriethylam-monium phosphate and 1 mM etidronate 8 92, apparent pH 6.25 B MeCN ll mM sodium phosphate containing 5 mM 1-octyltriethylammonium phosphate and 1.1 mM etidronate 13 87, apparent pH 6.25 Flow rate 1 

Internal standard 2-(3-p5rridinyl)oxy-l-hydroxymethane diphosphonic acid tetraam-monium salt (23) 

Vallano, P.T. Shugarts, S.B. Kline, W.F. Woolf, E.J. Matuszewski, B.K. Determination of risedronate in human urine by column-switching ion-pair high-performance liquid chromatography with ultraviolet detection, J.Chromatogr.B, 2003, 794, 23-33. 

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The hydration state of risedronate sodium was monitored continuously in a fluidized bed dryer and correlated to data on the physical stability of tablets made from the monitored material [275]. The final granulation moisture was found to affect the solid-state form, which in turn dictated the drug s physical stability over time. The process of freeze-drying mannitol was monitored continuously with in-line Raman and at-line NIR spectroscopies [276]. The thin polymer solvent coatings, such as poly(vinyl acetate) with toluene, methanol, benzene, and combinations of the solvents, were monitored as they dried to generate concentra-tion/time profiles [277]. 

Actonel contains risedronate sodium, a bisphosphonate. Osteonecrosis of the jaw has been reported in patients receiving oral bisphosphonates. Adequate oral hygiene should be maintained during and after treatment with bisphosphonates, including Actonel. Preventive dental treatment should be considered before starting bisphosphonates. Patient should be advised to maintain adequate oral hygiene during treatment. 

Bisphosphonates alendronate sodium clodronate disodium etidronate disodium pamidronate disodium risedronate sodium zoledronic acid... 

Common Name Risedronate sodium Structural Formula ... 

Risedronate sodium is a bisphosphonate that inhibits normal and abnormal bone resorption. It is indicated in the treatment of osteoporosis in postmenopausal women the prevention of osteoporosis in postmenopausal women at risk of developing osteoporosis the prevention and treatment of glucocorticoid-induced osteoporosis in men and women and in the treatment of Paget s disease of the bone. 

Aotonel NE-58096 Risedronate sodium Risedronic acid monosodium salt. Calcium regulator, used as a bone resorption inhibitor in treatment of osteoporosis, Merck Co.Inc. Procter Gamble Pharm. Inc. 

Actonel (Risedronate sodium). Procter Gamble Pharmaceuticals UK Limited UK Summary of product characteristics, October 2006. 

Example risedronate sodium In the US in 2009, the manufacturer agreed to reimburse for the costs of treating-related fractures. 

Fazil, M., Hassan, M.Q., Baboota, S., Ah, J., 2015. Biodegradable intranasal nanoparticulate drug delivery system of risedronate sodium for osteoporosis. Drug Deliv. 25, 1—11. 

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