Rifampicin Aminophylline

Clinically important, potentially hazardous interactions with aminophylline, aspirin, carbamazepine, clarithromycin, cyclosporine, daclizumab, erythromycin, itraconazole, ketoconazole, live vaccines, oral contraceptives, phenobarbital, rifampicin, rifampin, troleandomycin, warfarin... [Pg.374]

The AUC of theophylline (given as sustained-release aminophylline 450 mg) was redueed by 18% in 7 healthy subjects who took rifampicin 600 mg daily for one week. A parallel study in another 8 healthy subjects given the same dosage of rifampicin showed that the metabolic clearance of theophylline (given as intravenous aminophylline 5 mg/kg) was increased by 45%. ... [Pg.1196]

Similarly, other studies in healthy subjects given oral or intravenous theophylline or intravenous aminophylline and rifampicin 300 to 600 mg daily for 6 to 14 days found 25 to 82% rises in theophylline clearance, and... [Pg.1196]

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