Riboflavin dichloro

Oat (Avena sativa) extract Pantothenic acid Pyridoxine Riboflavin 5 -phosphate vitamin A determination 1,3-Dichloro-2-propanol vitamin A mfg. 

In the s3mthesis of riboflavin and some related flavins, better yields are often available through the use of 5-chloro- or 5,5-dichlorobarbituric acid place of alloxan. In addition to riboflavin, 6-methyl-9-2 i, y-methyl-g- s, 6-ethyl-9-3 , 7-ethyl-9-2 , 6,7-diethyl-9- , 6-ethyl-7-methyl-9-2 .3 , 5,7-di-niethyl-9- , 6,8-dimethyl-9- , 6,7-dichloro-9-29.72 6-chloro-9-3 -, 6-flu-oro-9-3 , 6,7-dibromo-9- , 5,6-dimethyl-9- , 6-chloro-7-methyl-9-2 , 6-meth-yl-7-chloro-9-, 3,6,7-trimethyl-9-(i -D-ribityl)isoalloxazine2 (using 2-methylalloxan), and 6,7-dichloro-9-(i -D-sorbityl)isoalloxazine i have been prepared by this method. 

Acyl CoA Dehydrogenases. Reaction (2) is catalyzed by a family of related enzymes. The lower fatty acid derivatives are oxidized by an enzyme purified from beef liver mitochondria. The isolated enzyme, butyryl dehydrogenase, has been reported to contain both riboflavin and copper.The nature of this enzyme will be discussed later in conjunction with other flavin enzjnmes. Chains of 3 to 8 carbons are oxidized in the presence of suitable electron acceptors, including 2,6-dichloro-phenolindophenol, cytochrome c, and ferricyanide. The maximum rate is obtained with butyryl CoA. It has been reported that the initial oxidation of fatty acid-CoA and the reduction of the employed electron acceptors are carried out by two different flavoproteins, which react with each... 

In relation to the concept that l,2-dimethyl-4,5-diaminobenzene is a metabolic precursor of riboflavin and cyanocobalamin, and the dichloro analog an antimetabolite, the signiflcance of all these findings is not readily apparent. Clearly, certain microorganism s can build several alternative nucleotides into the B12 molecule, and for them, dimethyl-diaminobenzene cannot be pictured as a specific metabolic precursor. Nor can its dichloro analog be regarded as an antimetabolite, at least in relation to the synthesis of vitamin B12 if, as it seems, it is readily utilized for the synthesis of a highly active form of the vitamin. 

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