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Retinoblastoma Gene and the Cell Cycle

Gene Name Familial Cancer Syndrome Protein Function Sites/Types of Commonly Associated Neoplasms [Pg.583]

ATM Ataxia telangiectasia Response to dsDNA breaks Leukemias, lymphomas [Pg.583]

BRCA1/BRCA2 Hereditary breast cancer Repair of dsDNA breaks Breast, ovarian [Pg.583]

MSH2 Human non-polyposis colon cancer DNA mismatch repair Colon, uterus [Pg.583]


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