Resveratrol cytotoxic effects

The plant family Dipterocarpaceae is comprised of three subfamilies, Dipterocarpoideae, Monotoideae, and Pakaraimoideae. Species of the largest subfamily, Dipterocarpoideae, are of most interest because of their economic use in producing timber and oleoresins. Plants of the Dipterocarpoideae are typified as sources of oligostilbenoids (resveratrol oligomers) which have shown various biological activities such as antibacterial, antifungal, anti-HIV antiviral, and cytotoxic effects. This... 

Additionally, several reports indicate that -resveratrol inhibits the proliferation of a wide variety of human cancer cells including breast, prostate, colon, gastric, lung, pancreatic, liver, thyroid, and ovarian cancers, leukemia, lymphoma, osteosarcoma, squamous cell carcinoma, multiple myeloma, and medulloblastoma [135]. Among the other stilbenoids, piceatannol, a- and s-viniferin, hopeaphenol, pallidol, ampelopsin A, vaticanol B and C, and pterostilbene also showed cytotoxicity and/or antiproliferative effect on different tumor cell lines [136-145]. 

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