Response surfaces, Color Plate

Note These equations are from Doming, S. N. Morgan, S. L. Experimental Design A Chemometric Approach. Elsevier Amsterdam, 1987, and pseudo-three-dimensional plots of the response surfaces can be found in their figures 11.4, 11.5, and 11.14. The response surface for problem (a) also is shown in Color Plate 13. 

FIGURE 12.1 Schematic representation of how the descriptor influence on each prediction can be extracted from the models response surface. The most significant descriptor fragment can then easily be highlighted in the structure for visual inspection. For color details, please see color plate section. 

Color Meter. The Chroma Meter CR-300 (Minolta, Osaka, Japan) provides both accurate and precise color data (Post et al., 1993). This color meter uses a pulsed xenon light for stable and uniform illumination of the sample. Three photocells measure the photons diifusely reflected by the sample through filters matching the CIE standard observer spectral response. A standard white plate is used for calibration. For analysis, the hand-held detector unit which is protected by a glass window may be placed on top of a small pile of a powdered sample (300 mg), thus standardizing the sample surface. This way, up to one hundred samples can be precisely measured within one hour. Further advantages are the mobility of the unit, and the output of the three color parameters in several color systems (see below). 

Fig. 1. Neurulation. (A) During the first phase of neurulation, naive uncommitted ectoderm is induced to form neural plate tissue via BMP inhibitory signals (noggin, chordin, follistatin) secreted from the underlying mesoderm. (B) During the second phase of neurulation the two halves of the open neural plate begin to curl up to form a hollow neural tube. During this time neural crest cells (ncc), which express Snail are induced at the neural plate border and begin to migrate in response to Wnt6 and Bmp expression in the surface ectoderm and dorsal neural tube respectively. (See Color Insert.)...

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