Response Factors of Non-isomeric Compounds

Using the protocol of this experimental procedure, determine whether the molar response factors, Mf, are identical for a pair of non-isomeric compounds, one of which is a hydrocarbon and the other of which contains a heteroatom, that have the same molecular weight. Possible examples might be (a) cyclohexane, (b) hexane and 2- or 3-pentanone, and (c) ethylbenzene and benzaldehyde. 

Pour any unused volatile organic compounds into the appropriate container for non-halogenated liquids or halogenated hydrocarbons put any mixture that contains a halogenated hydrocarbon in the container for halogenated hydrocarbons. 

Benzene (1 g, 12.5 mmol) is allowed to react with 1-chloropropane (1 g, 12.5 mmol) and AICI3. The product (1.2 g) is subjected to analysis on a GLC equipped with a thermal conductivity detector. The chromatogram shows two product peaks identified as n-propylbenzene (area = 65 mm = 1.06) and isopropylbenzene (area = 113 mm = 1.09). Calculate the percent yield of each of the two isomeric products obtained in this reaction. Note that since each of the products has the same molar mass of 120, the use of weight factors gives both weight and mole percent composition. 

A gas chromatogram of the organic components of a sample of beer using a column that separates compounds on the basis of their relative boiling points provides a GLC trace with several peaks. Two of the smaller peaks, with retention times of 9.56 and 16.23 minutes, are believed to be ethyl acetate and ethyl butyrate, respectively 

In the Olympics and other major athletic competitions, a GC-MS is used to screen athletes for their use of banned substances such as steroids (see Historical Highlight). If an analytical method has been developed and the retention time for a particular anabolic steroid has been determined, how might you use this method to determine the possibility of the use of anabolic steroids by an athlete  

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