Renal Toxicity Reasons for Poor Translation from Animal to Human

2 Renal Toxicity Reasons for Poor Translation from Animal to Human 

ANIMAL MODELS OF DISEASE FOR FUTURE TOXICITY PREDICTIONS 

3 Available Renal Models to Predict Renal Toxicity or Understand Molecular Mechanisms of Toxicity Advantages and Limitations 

Among various models, rodents are most frequently used as preferred animal models for understanding the complex pathophysiological responses associated with the development and progression of kidney diseases in humans. These models 

Immme-Mediated Glomerular Disease Animal models have been crucial to the understanding of immune-mediated glomerular disease in humans. Several animal models have developed using injection of preformed antibodies to 

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