Renal physiology biochemistry

Berndt, W. O. 1976. Renal function tests What do they mean A review of renal anatomy, biochemistry and physiology. Environmental Health Perspectives 15 55-71. 

Three main models have been used. The intact isolated perfused rat kidney (IPRK), is the most widely used model and first developed for the study autoregulation by Weiss et al in [262]. However, this prototype was little used initially because autoregulation and function declined after only 15-30 minutes. However, when simpler surgery and improved perfusion solutions were introduced by Ross, the model became useful for studies of renal biochemistry [263, 264]. With further improvements, including the addition of amino acids [265,266] and sometimes erythrocytes [267-269] the model became useful for studies of physiology and... 

RENAL BIOCHEMISTRY AND PHYSIOLOGY PATHOPHYSIOLOGY AND ANALYTICAL PERSPECTIVES... 

Figure 9.6 Nucleoside transporters in renal proximal tubule cells. Basolateral uptake proceeds by facilitated transport (bidirectional) via equilibrative nucleoside transporters (nENT 1, hENT2). At the luminal membrane, concentrative nucleoside transporters (CNT1-3) mediate nucleoside reabsorption via cotransport with sodium. Additionally, a role of ENTs at the brush border membrane has been proposed. Reprinted from Biochemistry and Cell Biology, Volume 84, A.N. EIwi, V.L. Damaraju, S.A. Baldwin, S.D. Young, M.B. Sawyer, and C.E. Cass, Renal nucleoside transporters Physiological and clinical implications, pp. 844 58, Copyright 2006, with permission from the NRC Research Press.

M. B., Cass, C. E. (2006). Renal nucleoside transporters Physiological and clinical implications. Biochemistry and Cell Biology = Biochimie et Biologie Cellulaire, 84, 844—858. 

Holmes, E., F. W. Bonner, and J. K. Nicholson. 1997. H NMR spectroscopic and histo-pathological studies on propylene-induced renal papillary necrosis in the rat and the multimammate desert mouse (Mastomys natalensis). Comparative Biochemistry and Physiology 116C 125-134. 

Field, Michael J., Carol Pollock, and David Harris. The Renal System Systems of the Body Series. 2d ed. New York Churchill Livingstone, 2010. Covers the basic anatomy, physiology, and biochemistry of the renal and urogenital system. 

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