REMARK records

Bobrov et al. have, remarkably, recorded the Raman spectrum of ethyne adsorbed at 80 K on evaporated films of Ni, showing shifted v= CH and vC=C bands at 3300 and 1860 cm"1, respectively. They also recorded bands at 3080, 3030, and 1525 cm"1, which they assigned to 77-bonded ethene (76). 

Here are some of Hooke s pregnant remarks, recorded in his Microgrt fhiaz Air is the menstruum or universal dissolvent of all sulphureous [combustible] bodies.. . . The dissolution of sulphureous bodies is made by a substance inherent, and mixt with the Air, that is like, if not the very same, with that which is hxt in Saltpeter.. .. In this dissolution of... 

The original PDB file is a rich source of information for a modeler. Crystallographers do not intentionally include errors in structures often, there will be known issues in the structure, which the crystallographer will have reported. Crystallographers include REMARK records in PDB files that can inform the reader of this. 

Figure 4.6 Remark records taken from PDB ID 2cdz showing information regarding missing atoms and missing residues.

The MMDB database can be searched from the NCBI home page using Entrez. (MMDB is also referred to as the NCBI Structure division.) Search helds in MMDB include PDB and MMDB ID codes, free text from the original PDB REMARK records, author name, and other hihliographic helds. Eor more specihc, helded queries, the RCSB site is recommended. 

The fight against HIV infection is another important field where fluorinated diazines have remarkable record, including approved drug Emricitabine (8) and 7 compounds that have reached clinical development phase (compounds 125-131) (Table 3). All these compounds act as HIV reverse transcriptase inhibitors and fall into two categories fiuorocytidine analogues (8 and 125-127) and trifluoromethyl-substituted quinazolone derivatives (128-131). 

To this category belong only two record types JRNL and REMARK, which in turn have their own detailed inner structures. Examples of the two records types arc presented later. 

The REMARK 4-999 records contain other optional, but predefined, remarks, As shown above, the "REMARK 4 record specifies that the analyzed file conform fully with, the current (December 2002) version 2.2 of the PDB file format specification. 

The temperature factor (together with the Cartesian coordinates) is the result of the rcfincincnt procedure as specified by the REMARK 3 record. High values of the temperature factor suggest cither disorder (the corresponding atom occupied different positions in different molecules in the crystal) or thermal motion (vibration). Many visualisation programs (e.g., RasMol [134] and Chime [155]) have a special color scheme designated to show this property. 

Every effort has been made to select the most reliable information and to record it with accuracy. Many years of occupation with this type of work bring a realization of the opportunities for the occurrence of errors, and while every endeavor has been made to prevent them, yet it would be remarkable if the attempts towards this end had always been successful. In this connection it is desired to express appreciation to those who in the past have called attention to errors, and it will be appreciated if this be done again with the present compilation for the publishers have given their assurance that no expense will be spared in making the necessary changes in subsequent printings. 

REMARKS (1) Record Basis of Observation in Space Provided. 

In view of the strychnine-like pharmacological action recorded for gelsemine, Janot and Berton have compared the ultra-violet absorption spectra of the two alkaloids, which proved to be remarkably similar. That of sempervirine was quite different and also unlike those of indole, quinoline and cinchonamine, with which it was also compared. 

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