REM-TrEMBL

The SWISS-PROT and TrEMBL ID lines differ in the first two parts of the ID line. The first part is the entry name "ANP NOTCO" in the case of the SWISS-PROT example and "Q12757" in the TrEMBL example. The entry name used in all SP-TrEMBL entries is always the same as the accession number of the entry. The entry name used in REM-TrEMBL is the Protein ID tagged to the corresponding CDS in the EMBL Nucleotide Sequence Database. To the right of the entry name you will find either "preliminary" (in the TrEMBL entry) or STANDARD (in the SWISS-PROT entry). The data class used in TrEMBL is always PRELIMINARY. That means that the data are thoroughly checked by a computer,... 

The entries from the composite divisions of the EMBL database (HTG, STS, EST, and UNC) are now added to their relative taxonomic TrEMBLnew divisions. Then all hies are searched for entries that have recently been added to SWISS-PROT or TrEMBL and are thus missing a /dbxref = SWISS-PROT or a /dbxref = SPTREMBL qualifier in EMBL. These entries are removed. The entries put in the hies patent.dat, immuno.dat, smalls.dat, synthetic.dat and pseudo.dat are now already at the end of their production line. They are new entries in REM-TrEMBL (REMaining TrEMBL), which contains the entries (about 44,000 in release 10) that will not be included in SWISS-PROT. This section is organized in hve subsections ... 

Immunoglobulins and T-cell receptors (hie name Immuno.dat) Most REM-TrEMBL entries are immunoglobulins and T-cell receptors. The integration of additional immunoglobulins and T-cell receptors into SWISS-PROT has been stopped, because SWISS-PROT does not want to add all known somatic recombined variations of these proteins to the database. Currently there are more than 18,000 immunoglobulins and T-cell receptors in REM-TrEMBL. SWISS-PROT plans to create a specialized database dealing with these sequences as another supplement to SWISS-PROT but will keep only a representative cross section of these proteins in SWISS-PROT. 

The weekly updated SP-TrEMBL work release. REM-TrEMBL is not included in SP TR NRDB because REM-TrEMBL contains the entries that will not be included in SWISS-PROT, e.g., synthetic sequences and pseudogenes. 

Translated EMBL (TrEMBL) was created as a computer-annotated supplement to SWISS-PROT (Bleasby et al, 1994) having two main sections. SP-TrEMBL contains entries that are eventually incorporated into SWISS-PROT but not yet been manually annotated. REM-TrEMBL contains sequences that are not destined to be included in SWISS-PROT, including T-cell receptors, fragments of fewer than eight amino acids,... 

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