Relative chirality indices

Relative chirality indices (vRCl) for a pair of enantiomers are calculated as... 

Relative chirality indices and chirality correction factors forthe two enantiomers shown below, together with valence vertex degrees and first-order valence connectivity index of the functional groups. 

To calculate the relative chirality index, the least important chemical group (d) is placed at the rear, and the clockwise and anticlockwise arrangement of the other three groups (a, b, c) are used to represent the R- and S-configurations, respectively. 

Which pair of enantiomers of Figure 34 is most chiral Flow will we decide, when the relative magnitudes for the similarity/dissimilarity depend on the length of the window used for the comparison One way to obtain a single index for the measure of chirality is to add all of the entries in each row and view the total as the measure of chirality. The last column of Table 32 lists the total up to the windows of length 16. If we are to extend the table to the maximal paths of length 22, the relative values would not change since the additional values are all constant. From the last column of Table 32 we can read as the most chiral ... 

There are a large number of LC detectors available but, of these, a relatively few are in common use. This is largely because some detectors are highly specific and others are very expensive. About 95% of all LC analyses are carried out using one of 5 different types of detectors, the UV adsorption detector, the fluorescence detector, the electrical conductivity detector, the light scattering detector and the refractive index detector. However, in addition to these basic detectors, for obvious reasons an example of a chiral detector will also be included. 

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