Regulons

Baldwin, T. O., et al. (1989). The complete nucleotide sequence of the lux regulon of Vibrio fischeri and the luxABN region of bacterial bioluminescence. ]. Biolumin. Chemilumin. 4 326-341. 

Christman, M.F., Morgan,R.W., Jacobson, F.S., Ames, B. (1985). Positive control of a regulon for defenses against oxidative stress and some heat shock proteins in Salmonella typhimurium. Cell 41, 753-762. 

It transpires that the heat shock genes of one single bacterial species are regulated by different mechanisms. Genes and operons controlled by one particular regulator are called regulons and, if there are at least two regulons in one species induced by the same stress factor, they form a stimulon. 

Fig. 2. Modulation of the RseA activity a working model. In the absence of non-native proteins in the periplasm, is bound to the RseA anti-sigma factor this binding is stabilized by RseB, a co-anti-sigma factor, in the periplasm. Upon accumulation of non-native proteins within the periplasm, RseB is released followed by dissociation of which interacts with RNA polymerase core enzyme to initiate transcription of the heat shock genes of the sigma-E regulon...

Schultz AC, P Nygaard, HH Saxild (2001) Functional analysis of 14 genes that constitute the purine catabolic pathway in Bacillus subtilis and evidence for a novel regulon controlled by the PucR transcription activator. J Bacteriol 183 3293-3302. 

Jiang W, WW Metcalf, K-S Lee, BL Wanner (1995) Molecular cloning, mapping, and regulation of the pho regulon genes for phosphonate breakdown by the phosphonatase pathway of Salmonella typhimurium LT2. J Bacteriol 111 6411-6421. 

Wackett LP, BL Wanner, CP Venditti, CT Walsh (1987b) Involvement of the phosphate regulon and the psiD locus in carbon-phosphorus lyase activity of Escherichi coli K-12. J Bacterial 169 1753-1756. 

Gaudu, P., Moon, N., and Weiss, B. 1997. Regulation of the soxRS oxidative stress regulon. The Journal of Biological Chemistry 272 5082-5086. 

HTHLUXR helix turn helix, Lux regulon E()B 0(0) 0(0) 1A04... 

Opel ML, Arfin SM, Hatfield GW (2001) The effects of DNA supercoiling on the expression of operons of the ilv regulon of Escherichia coli suggest a physiological rationale for divergently transcribed operons. Mol Microbiol 39 1109-1115... 

The formate regulon of E. coli bye genes encoding structural components of the hydrogenase 3... 

The hydrogenase 3 of E. coli is part of the formate hydrogen lyase complex (FHL) whose corresponding genes are organized in the formate regulon (Fig. 3.2) (Rossmann et al. 1991). Hydrogenase maturation proteins are encoded by the... 

Rossmann, R., Sawers, G. and Bock, A. (1991) Mechanism of regulation of the formate-hydro-genlyase pathway by oxygen, nitrate, and pH Definition of the formate regulon. Mol. Microbiol., 5, 2807-14. 

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