Registration phase

Drugs can be administered after the registration phase with the purpose of studying their action on encoding processes. Trials of this type in humans are difficult to interpret, mainly because encoding processes of various types and levels may last for seconds, minutes or hours, whereas the time at... 

Administration after the registration phase, at the time of encodng. 

The Registration phase of REACH and the Principles of Chemical Leasing business models have additional central aspects in common. They both involve different stages of the supply chain - as producers and applicants are challenged - and both approaches are life-cycle oriented either through their documentation requirements addressing phases of production, use or dis-... 

The registration phase as such does not necessarily lead to reduced risks, and the quality of the data generated is not guaranteed. The ECHA is merely required to make a completeness check within three weeks (Article 20), after which the chemical in question can be used. 

Strict demands on general and early substitution substitutes should be identified for substances in high quantities or with dangerous properties already in the registration phase. 

The Agency intends to publish a list of all pre-registered substances on its website one month after the deadline of 18 months. This pre-registration phase will probably start in Summer 2008 and continue until the end of 2009 (source publication of the European Council in March 2006). All manufacturers or importers of such pre-registered phase-in substances in quantities of less than 1 tonne per year, as well as downstream users and third parties, have to submit to the Agency the same information as that required from the pre-registrants. 

A review of the scientific literature produced the last 10 years (1982-1992) provides a panorama of the state of affairs with GVs for insect control. The research and development of GVs, like that of other pest control agents, follows a pattern and a progression. In this chapter, I have chosen to organize the current state of research and development of GVs into three phases (1) Exploratory Phase (2) Preregistration Phase and (3) Registration Phase. 

The Registration Phase. This phase encompasses candidate GVs that have demonstrated sufficient promise to merit consideration for registration and commercialization. It is the final and necessary phase that all microbial agents which are to be... 

The Registration Phase in the USA. In 1980, the UCB-CpGV Program headed by L. Falcon, provided Sandoz, Inc., USA, with CpGV and start-up technology. San-doz developed an experimental product labelled "SAN 406" and USEPA issued an EUP with an exemption from a tolerance for it in 1981. The product received wide distribution and was tested by several researchers in more than two dozen orchards in the USA (59) and Canada (57) and 10 European countries (56) from 1981... 

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