Regenerative medicine hydrogelators

Slaughter BV, Khurshid SS, Fisher OZ et al (2009) Hydrogels in regenerative medicine. Adv Mater 21 3307-3329... 

Cross-linked cyclic polyacetals have been examined in recent years for use in regenerative medicine [125] in an effort to minimize the inflammatory response often caused by degradation side products (e.g., acids from polyesters). One example is the copolymer hydrogel poly[poly(ethylene glycol)-ct -cyclic-acetal] 42 (Figure 13.8). The diol 39 is prepared from trimethanol... 

Pape A, Dankers P (2015) Supramolecular hydrogels for regenerative medicine. In Seifftut S (ed) Supramolecular polymer networks. Advances in Polymer Science. Springer, Cham... 

Keywords Biomedical applications Regenerative medicine Supramolecular hydrogels Translational research... 

The use of supramolecular hydrogels in regenerative medicine is inspired by the extracellular matrix (ECM), which provides the natural scaffolding for cells inside the body [14]. Mimicking the ECM is a major objective for tissue engineering, in order to create a regenerating niche for cells [15]. The natural ECM is inherently... 

Low molecular weight hydrogelators form one-dimensional (ID) stacks and, subsequently, gel networks in water. The behavior of these molecules in organic solvents is well known, and the ability to tune these materials lies in the power of the chemistry to be scalable. Therefore, we consider these materials promising for application in regenerative medicine and give a few examples. 

Skardal A (2014) Extracellular matrix-like hydrogels for applications in regenerative medicine. In Connon CJ, Hamley IW (eds) Hydrogels in cell-based therapies. Royal Society of Chemistry, Cambridge, doi 10.1039/9781782622055-00191... 

Chitosan is one of the widely used biomaterials and has gained considerable attention in tissue engineering and regenerative medicine applications in recent decades. The importance comes from its biocompatibility, biodegradability and easy availability, as well as the possibility to be prepared in various forms such as films, membranes, nanoparticles, fibers, hydrogels and scaffolds. Chitosan is a linear polysaccharide and is obtained... 

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