Redox-activated reactions chemically reactive species

Aging is accompanied by increases in the redox active metals iron (Fe) and copper (Cu). The significance of this is that the great majority of chemical radical and reactive oxygen species/reactive nitrogen species (ROS/RNS) are generated by a reaction catalyzed by these transition metals [12]. Damage by radical attack and ROS/RNS is abundantly apparent in AD-affected... 

Modern electrochemical methods provide the coordination chemist with a powerful means of studying chemical reactions coupled to electron transfer and exploiting such chemistry in electrosynthesis. In addition, the electrochemical generation of reactive metallo intermediates can provide routes for the activation of otherwise inert molecules, as in the reduction of N2 to ammonia,50 and for electrocatalyzing redox reactions, such as the reduction of C02 to formate and oxalate,51 the oxidation of NH3 to N02-,52 and the technologically important oxidation of water to 02 or its converse, the reduction of 02 to water.53 Electrochemical reactions involving coordination compounds and organometallic species have been extensively reviewed.54-60... 

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