Receptors as targets

Cato AC, Schacke H, Sterry W, Asadullah K. (2004) The glucocorticoid receptor as target for classic and novel anti-inflammatory therapy. Curr Drug Targets Inflamm Allergy. 3, 347-353. 

Gunthorpe Ml, Szallasi A. (2008) Peripheral TRPV1 receptors as targets for drug development New molecules and mechanisms. Curr Pharm Des 14 32-41. 

Parsons CG (2001) NMDA receptors as targets for drng action in nemopathic pain. Em J Pharmacol 429 71-78... 

R. A. Glennon (1987). Central serotonin receptors as targets for drug research. J. Med. Chem. 30 1-12. 

Fredholm BB (2003) Adenosine receptors as targets for drug development. Drug News Perspect 16(5) 283-289... 

Hoffmann J, Sommer A. Steroid hormone receptors as targets for the therapy of breast and prostate cancer— recent advances, mechanisms of resistance, and new approaches. J Steroid Biochem Mol Biol. 2005 93 191-200. 

The Emergence of 5-HT2B Receptors as Targets to Avoid in Designing and Refining Pharmaceuticals... 

HT6 Receptors as Targets for the Treatment of Cognitive Deficits in Schizophrenia... 

Patacchini R, Maggi CA (2001) Peripheral tachykinin receptors as targets for new drugs. Eur J Pharmacol 429 13-21... 

There is increasing evidence for the involvement of CRF in a number of neurological and inflammatory disorders, and hence interest in manipulation of CRF and its receptors as targets in novel drug development. 

The lack of selective muscarinic receptor ligands has for a long time limited the definition of therapeutic treatment based on muscarinic receptors as targets. Some muscarinic ligands such as cev-imeline or xanomeline have been developed for the treatment of AD and other CNS disorders. Some muscarinic agonists (vedaclidine) have analgesic effects comparable to those produced by morphine or opiates [194],... 

Makishima, M. (2005) Nuclear receptors as targets for drug development regulation of cholesterol and bile acid metabolism by nuclear receptors. Journal of Pharmacological Sciences, 97, 177-183. 

Flolladay, M.W., Dart, M.J., Lynch, J.K., 1997. Neuronal nicotinic acetylcholine receptors as target for drug discovery. J. Med. Chem. 40, 4169-4194. 

Silvia M. Kreda, Raymond J. Pickles, Eduardo R. Lazarowski and Richard C. Boucher, G-protein-coupled receptors as targets for gene transfer vectors using natural small-molecule ligands. Nature Biotechnology, 18 (2000), 635-640. 

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