Receptor phosphorylation and

Zhang L, Yunkai Y, Mackin S et al. Differential p opiate receptor phosphorylation and desensitization induced by agonists and phorbol esters. J Biol Chem 1996 271 11449-11454. 

A paper detailing the properties of the multikinase inhibitor ABT-869 (7) did not indicate whether plasma protein binding data were used in the optimization leading to this highly protein-bound (mouse 98.2%, human 99.0%) compound [45]. A dose which provided a 69% reduction in tumor growth and >50% inhibition of receptor phosphorylation and pharmacodynamic response afforded plasma concentration that remained above the cellular IC50 for receptor phosphorylation in the presence of plasma for 4 of 12 h in the bid dosing cycle. 

I. A. Hanover, R. B. Dickson (1985). The possible hnk between receptor phosphorylation and... 

Krasel, C., Bunemann, M., Lorenz, K., and Lohse, M. J. (2005). /J-Arrestin binding to the / -adrenergic receptor requires both receptor phosphorylation and receptor activation. J. Biol. Chem. 280, 9528-9535. 

Backstrom JR, et al. Deletion of the serotonin 5-HT2C receptor PDZ recognition motif prevents receptor phosphorylation and delays resensitization of receptor responses. J Biol Chem 2000 275(31) 23,620-23,626. 

HT2C MUPP1 Facilitates receptor phosphorylation and resensitization Carboxyl terminus PDZ domain 238, 240, 241... 

Wang, D., Yu, X., Cohen, R.A., and Brecher, P. 2000. Distinct effects of N-acetylcysteine and nitric oxide on angiotensin II-induced epidermal growth factor receptor phosphorylation and intracellular Ca2+ levels. J. Biol. Chem. 275 12223-12230. 

Esposito, F., G. Chirico, G.N. Montesano, I. Posadas, R. Ammendola, T. Russo, G. Cirino, and F. Cimino. 2003. Protein kinase B activation by reactive oxygen species is independent of tyrosine kinase receptor phosphorylation and requires SRC activity. J. Biol. Chem. 278 20828-20834. 

A Core-Box Model for Insulin Receptor Phosphorylation and Internalization in Adipocytes... 

Fraser ID, Cong M, Kim J, et al. Assembly of an A kinase-anchoring protcin-jL-adrenergic receptor complex facilitates receptor phosphorylation and signaling. Curr Biol 2000 10 409 112. 

Mendel DB, Schreck RE, West DC, Li G, Strawn LM, et al. 2000. The angiogenesis inhibitor SU5416 has long-lasting effects on vascular endothelial growth factor receptor phosphorylation and function. Clin. Cancer Res. 6 4848-58... 

J. R. ZiERATH, J.N. Livingston, and A. Thorne, et al., Regional difference in insulin inhibition of non-esterified fatty acid release from human adipocytes relation to insulin receptor phosphorylation and intracellular signalling through the insulin receptor substrate-1 pathway, Diabetologia, 1998, 41, 1343-1354. 

Goldkom, T. et al., EGF-receptor phosphorylation and signaling are targeted by H202 redox stress, Hw. J. Respir. Cell Mol Biol, 19,786, 1998. 

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