Reactors for Large-Scale Animal Cell Culture

3 Reactors for Large-Scale Animal Cell Culture 

1 Stem Cell Engineering hi the overall field of biotherapeutics, stem cell engineering is a major area of current research. In view of its growing importance, a brief overview of this subject is presented in the following. 

EMBRYONIC STEM CELLS A fertilized egg divides to form two cells. This binary division process continues till amass of-150 cells is formed. This mass called blastocyst consists of two regions the outer shell and an inner cell mass encapsulated by the outer shell. It is possible to extract this inner cell mass. The extracted mass can be cultured to create stem cells. These stem cells are pluripotent, a term indicative of their multiple potencies for forming any cell type under the proper impulse. 

STIRRED TANK REACTORS FOR CELL CULTURE TECHNOLOGY 

INDUCED PLURIPOTENT (iPS) CELLS These ceUs are mature, somatic, non-germline-type cells. They can be derived from, for example, skin on the hand. In culture systems, these cells can be converted to the stem cell variety. Once converted to the latter state, they can differentiate into the desired mature cell type of the body. Reprogramming with three or four properly chosen genes can induce pluripotency in the mature stem cells. Successful research in this area has been acknowledged through the Nobel Prize for 2012 in physiology or medicine jointly awarded to John 

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B.2.3 Reactors for Large-Scale Animal Cell Culture... 

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