Reaction with ArCH

CH3CH=CHCH2ZnCl Reaction with ArCH=CH2 5.7.2.4.2 C4H2HgIO... 

The triazole 76, which is more accurately portrayed as the nucleophilic carbene structure 76a, acts as a formyl anion equivalent by reaction with alkyl halides and subsequent reductive cleavage to give aldehydes as shown (75TL1889). The benzoin reaction may be considered as resulting in the net addition of a benzoyl anion to a benzaldehyde, and the chiral triazolium salt 77 has been reported to be an efficient asymmetric catalyst for this, giving the products (/ )-ArCH(OH)COAr, in up to 86% e.e. (96HCA1217). In the closely related intramolecular Stetter reaction e.e.s of up to 74% were obtained (96HCA1899). 

Denicola A, Freeman BA, Trujillo M, Radi R (1996) Peroxynitrite reaction with carbon dioxide/bicar-bonate kinetics and influence on peroxynitrite-mediated oxidations. Arch Biochem Biophys 333 49-58... 

The electronic nature of the groups attached to the anionic carbon also affects the proportion of C-alkylation. The amount of C-alkylation in the reaction of ArCH( -Bu)Cl with a series of a-methylated carbanions, having similar steric interactions, decreases when the stabilizing substituents on the carbanion are changed from cyano to alkoxycarbonyl and to acetyl. 

L13. Lehnig, M., Radical mechanisms of the decomposition of peroxynitrite and the peroxynitrite-CO(2) adduct and of reactions with 1-tyrosine and related compounds as studied by (15)N chemically induced dynamic nuclear polarization. Arch. Biochem. Biophys. 368, 303-318... 

Sakakura A, Suzuki K, Nakano K, Ishihara K (2006) Chiral l,l -binaphthyl-2,2 -diammonium salt catalysts for the enantioselective Diels-Alder reaction with a-acyloxyacroleins. Org Lett 8 2229-2232 Sanwal BD, Zink MW (1961) L-Leucine dehydrogenase of Bacillus cereus. Arch Biochem Biophys 94 430-435... 

Reaction with nitmalkanes. The reaction of primary and secondary nitroalkanes with ISi(CH,) i (2 equiv.) results in formation of the corresponding oximes as the major product. However, benzylic nitroalkanes, ArCH,NOj, are converted into nitriles in high yield. 

Means, G.E., Wu, H.L. (1979). The reactive tyrosine residue of human serum albumin characterization of its reaction with diisopropylfluorophosphate. Arch. Biochem. Biophys. 194 526-30. 

Mehler, A. H. (1951). Studies on reactions ofUluminated chloroplasts. II. Stimulation and inhibition of the reaction with molecular oxygen. Arch. Biochem. Biophys. 33, 339—351. 

Zinner, G., Bock, W. Ugi-reactions with hydrazines. III. Ugi-reaction with diaziridines. Arch. Pharm. (Weinheim, Ger.) 1973, 306, 94-96. 

Park do Y, Kim JY, Ghi KU, et al. Gomparison of polymerase chain reaction with histopathologic features for diagnosis of tuberculosis in formalin-fixed, paraffin-embedded histologic specimens. Arch Pathol Lab Med. 2003 127 326-330. 

This potentially reactive intermediate may show an affinity for the oestradiol receptor and thereby accumulate in oestrogen target organs. This may facilitate reaction with DNA in these organs. From Metzler andMcLachlan (1979) Archs. Toxicol, Suppl. 2, 275. 

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