Rasagiline mesylate

In this section, we describe as typical examples the application of (R)-PGA as a chiral vehicle in the preparation of (5)-l-aminoindane3s (see also Chapter 24) and (,S )-3,3-dimethyl-2-butylamine. (S)-l-Aminoindane is present as a key structural element (or with additional functionalization) in therapeutic agents under clinical investigation [e.g., Rasagiline mesylate, (18) for the treatment of Parkinson s disease,39 and Irindalone (19), which displays potent antihypertensive activity].40... 

Rabey JM, Sagi I, Huberman M, et al. Rasagiline mesylate, a new MAO-B inhibitor for the treatment of Parkinson s disease A double-blind study as adjunctive therapy to levodopa. Clin Neuropharmacol 2000 23 324-330. 

Entacapone (Comtan) Pramipexole (Mirapex) Rasagiline Mesylate (AzUect)... 

As a low-dose active pharmaceutical ingredient, rasagiline mesylate was used. Flexible doses of the drug in a single unit can be... 

It was shown that rasagiline mesylate reaystaUizes on the surface of orodispersible films and transparency films, and the printed crystals are arranged in lines. No drug crystals were detected after printing on the surface of the copy paper due to the absorption of the ink into the matrix of the substrate. 

Hydroxypropyl methylcellulose (HPMC) (Pharmacoat 606) with crospovidone (Kollidon CL -M) rasagiline mesylate Solvent casting with inkjet printing 10,13,14 [17]... 

N. Genina, E.M. Janfien, A. Breitenbach, J. Breitkreutz, N. Sandler, Evaluation of different substrates for inkjet printing of rasagiline mesylate, European J. Pharm Biopharm, 85 1075-1083,2013. 

DKR of racemic amines for the synthesis of norsertraline and (/ )-rasagiline mesylate. 

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