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Raloxifene interaction with estrogen receptors

Raloxifene Interacts selectively with estrogen receptors Inhibits bone resorption without stimulating breast or uterus Osteoporosis Does not prevent hot flashes increased risk of thrombophlebitis... [Pg.974]

Schafer JI, Liu H, Tonetti DA, Jordan VC (1999) The interaction of raloxifene and the active metabolite of the antiestrogen EM-800 (SC 5705) with the human estrogen receptor. Cancer Res 59 4308-4313... [Pg.168]

Fig. 1 A deviation of only 20° in the dihedral of the selective estrogen receptor modulator raloxifene would result in a change of 2.5 A in the tertiary amine position, missing the favorable hydrogen-bond interaction with Asp351... Fig. 1 A deviation of only 20° in the dihedral of the selective estrogen receptor modulator raloxifene would result in a change of 2.5 A in the tertiary amine position, missing the favorable hydrogen-bond interaction with Asp351...
See other pages where Raloxifene interaction with estrogen receptors is mentioned: [Pg.31]    [Pg.41]    [Pg.224]    [Pg.321]    [Pg.147]    [Pg.378]    [Pg.85]    [Pg.300]    [Pg.313]    [Pg.9]    [Pg.711]    [Pg.711]    [Pg.1856]    [Pg.1068]    [Pg.348]    [Pg.145]    [Pg.195]    [Pg.98]   
See also in sourсe #XX -- [ Pg.3 , Pg.646 ]



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