Positron emitting radionuclide

Rb, as the rubidium ion (Rb+), is a potassium ion mimic and can be used to image viable myocardium. The development of an infusion generator makes this very-short-half-life (76 s) positron-emitting radionuclide useful.20,21... 

Table 1. Short-lived positron-emitting radionuclides for PET imaging...

S. Stone-Elander, N. Elander, Microwave applications in radiolabelling with shortlived positron-emitting radionuclides, J. Label. Compds Radiopharm. 45 (2002) 715-746. 

Our production parameters for this generator are presented. The Xe-122/l-122 combination, a convenient source of a short-lived (3.6m) positron emitting iodine, is also discussed. Recent developments in rapid iodination procedures will broaden the potential applications of this generator. Finally, preliminary investigations of another generator derived radionuclide that may have promise is described. Tellurium-118 (6d) is the parent of the 3.5 minute positron emitter Sb-118 which may be useful for first pass angiography. 

Three new positron emitting generator systems have been described. The practical availability of these radionuclides could significantly broaden the potential applications of positron emission tomography. The next few years should see human clinical trials undertaken to fully evaluate their utility for nuclear medicine. 

Somatostatin Analogs Labeled with Positron-Emitting Metal Radionuclides 183... 

Keywords Somatostatin Positron-emitting radionuclide Cancer therapy Diagnosis Positron emission tomography... 

Fig. 2 Structures of somatostatin analogs and halogen-labeling synthons for radiolabeling with halogen positron-emitting radionuclides...

Distribution in vivo could be studied by positron emission tomography (PET). Positron emission tomography is a sensitive and specific functional non invasive 3-D imaging method that permits rapidly and directly measurement of the total radioactivity from a drug labelled with a positron-emitting radionuclide (Gupta). 

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