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Radiochemical purity technetium

Racemization amino acids metal complexes, 467 Radioactive waste high level disposal, 895 Radiochemical purity technetium-99 in medicine, 976 Radionuclides... [Pg.7214]

Radiochemical purity determinations consist of separating the different chemical substances containing the radionuclide. The radiochemical purity of labeled pharmaceuticals is typically determined by paper chromatography (paper impregnated with silica gel or silicic acid). The most frequently used radioisotope is technetium-99m obtained by daily elution with saline... [Pg.294]

Shattuck LA, Eshima D, Taylor AT, Anderson TL, Graham DL, Latino FA, Payne SE (1994) Evaluation of the hepatobiliary excretion of technetium-99m-MAG3 and reconstitution factors affecting radiochemical purity. J Nucl Med 35 349-355... [Pg.142]

Kowalsky RJ, Dalton DR (1981) Technical problems associated with the production of technetium [ " Tc] tin(II) pyrophophate kits. Am J Hosp Pharm 38 1722-1726 Krishnamurthy GT, Huebotter RJ, Walsh CF, Taylor JR, Kehr MD, Tubis M, Blahd WH (1975) Kinetics of " Tc-labeled pyrophosphate and polyphosphate in man. J Nucl Med 16 109-115 Krogsgaard OW (1976) Radiochemical purity of various Tc-99m-labelled bone scanning agents. Eur J Nucl Med 1 15-17... [Pg.278]

Radiochemical Purity. The Ph. Eur. (Council of Europe 2005) requires paper chromatography using acetonitrile/water (60 40, v/v) to determine reduced, hydrolized technetium at the start, which should not exceed 2% of the measured radioactivity. For identification of Tc-mertiatide and Tc-Na-pertechnetate, high performance liquid chromatography (HPLC) is recommended. The radiochemical purity of the Tc-MAG3 complex should not be less than 94%. [Pg.311]

Methods Recommended by the Manufacturer. Thin-layer chromatography (TLC) on silica gel reversed phase plates (migration distance 10-15 cm) and acidified methanol-saline is used as solvent for the analysis of three components, namely the " Tc-MAG3 complex (R =0.4-0.5) reduced, hydrolized technetium at the start and unbound 99mTc-Na-pertechnetate at the solvent front. The radiochemical purity of the " Tc-MAG3 complex should not be less than 90%. [Pg.311]

Mallol J, Bonino C (1997) Comparison of radiochemical purity control methods for technetium radiopharmaceuticals used in hospital radiopharmacy. Nucl Med Com-mun 18 419-422... [Pg.344]

Jesus Mallol, Ph.D, September 1995 Comparison of radiochemical purity control methods for technetium radiopharmaceuticals used in hospital radiopharmacy. Sorin Bio-medica S.p.A., Radiopharmaceutical Development, Saluggia, Italy Martina Netter, M.Sc., 3-21 June 1996 Study of methods to enhance the stability of the " Tc-HM-PAO complex. Addenbrooke s Hospital, Cambridge, UK... [Pg.345]

See other pages where Radiochemical purity technetium is mentioned: [Pg.100]    [Pg.208]    [Pg.7185]    [Pg.100]    [Pg.208]    [Pg.7185]    [Pg.976]    [Pg.4]    [Pg.5476]    [Pg.976]    [Pg.989]    [Pg.4]    [Pg.316]    [Pg.341]    [Pg.380]    [Pg.5475]    [Pg.7121]    [Pg.2076]    [Pg.223]    [Pg.223]    [Pg.28]   
See also in sourсe #XX -- [ Pg.99 ]

See also in sourсe #XX -- [ Pg.99 ]

See also in sourсe #XX -- [ Pg.99 ]



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