RAC3, Receptor associated coactivator

Li H, Gomes PJ, Chen JD. 1997. RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2. Proc. Natl. Acad. Sci. USA 94 8479-84... 

ACTR/RAC3 and p/cip A receptor-associated cofactor 3 (RAC3) was cloned as a coactivator for the liganded receptor LBD (69) and found to be identical to another coactivator named ACTR, which was known to possess intrinsic HAT activity (70). Sequence comparison revealed a homology to the SRC-1 and TIFII members (69) therefore, it was also categorized in the SRC family. A closely related coactivator, the p300/CBP cointegrator associated protein (p/CIP), was found to interact with CBP and was required for the actions of CBP-dependent transcription factors (71). These members represent the third SRC family that functions as coactivators for RARs and RXRs, and possesses HAT activity. 

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