Quinoxalin-2-ones and Quinoxaline-2,3-diones

E. Reactions of Quinoxalin-2-ones and Quinoxaline-2,3-diones (2-Hydroxy- and 2,3-Dihydroxy-quinoxalines) ... 

With diazomethane, quinoxalin-2-ones and quinoxaline-2,3-diones form mixtures of N- and O-methyl derivatives. A consideration of... 

The chemistry of quinoxalin-2-ones and quinoxaline-2,3-diones (2-hydroxy- and 2,3-dihydroxyquinoxalines) has been previously reviewed by Simpson. Quinoxalin-2-ones are very easily prepared from condensation of o-phenylenediamines and a-keto acids and because of their ease of preparation, they have been used as characterizing derivatives for a-keto acids. There are widespread references in the patent literature to the preparation of quinoxalinones for potential pharmaceutical and horticultural applications and also for the formation of polymers. 

This chapter updates the earlier review in Simpson s monograph except that consideration of l,2-dihydro-2-oxoquinoxalines and 1,2,3,4-tetrahydro-2,3-dioxoquinoxalines has been transferred to Chapter V, which deals with quinoxalin-2-ones and quinoxaline-2,3-diones. ... 

---