Orthostatic hypotension quetiapine

Cardiovascular effects. Given aj-adrenergic receptor antagonism, quetiapine may induce orthostatic hypotension and concomitant symptoms of dizziness, tachycardia, and syncope. The risk of symptomatic hypotension is particularly pronounced during initial dose titration. Quetiapine should be used with caution in patients with cardiovascular disease, cerebrovascular disease, or other illnesses predisposing to hypotension. 

Quetiapine Sedation, mild weight gain, orthostatic hypotension 100 50-100 mg/day increments 600... 

Observational Studies A naturalistic study of first-episode psychosis outpatients treated with quetiapine reported fatigue, sedation, dizziness, followed by gastrointestinal disorders and nausea and orthostatic hypotension as the most frequent adverse events [203 ]. 

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