Quality perspectives

There are numerous examples where food extensional properties are relevant from the product quality perspective - some obvious examples include the extensibility of doughs, stretching of Mozzarella or Pizza cheese melts, extrusion-cooking of cereals, flow of honey and treacle. Overall, dough products have received the most attention. The importance of extensional viscosity in food processing has been reviewed by Escher (44 and references therein). 

This chapter has been divided into three distinct sections, all of which focus on a forward quality perspective to ensure that the highest level of quality assurance (QA) and durable compliance is maintained throughout the drug development process, during initial product launch, and after the product has been commercialized. 

There are myriad clinical issues that can benefit from a forward quality perspective and commitment. The entire process—from synthesizing a compound in the laboratory and establishing toxicology in animal studies to subsequent pharmacological and efficacy studies in human trials—offers opportunities for and legitimately requires QA. This is an enormously costly process (typically over 100 million) therefore, embracing a forward quality mindset from the onset of clinical development and throughout clinical trial activities is extremely beneficial. 

Embrace a forward quality perspective during the early stages of product development. 

Suggested Contract Content from a Compliance, Security, and Quality Perspective... 

Yaskanin, D. Quality Perspectives for Compound Storage, presented at the Drug Discovery Technology World Congress post-conference session on Repository Compound Stability Studies, Boston, MA, August, 2002. 

Hill, A. E. (2009). Microbiological stability of beer. In C. Bamforth (Ed.), Beer A quality perspective (pp. 163-184). Academic Press. 

From a solution quality perspective, it is typically advantageous to construct windows of the largest size that can be efficiently processed by a given optimization (e.g., see Table 8.1). In such cases, therefore, it is advantageous for windows to be of similar size. However, if efficiency concerns dictate that windows cannot overlap, some windows may have to be smaller. Also, some windows may represent well-formed clusters of logic (e.g., multipliers or decoders) that are only loosely connected to the remaining circuit. Such windows can also be smaller than maximal reasonable size. 

---