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Pyridines, example

We often speak of the PPP (Pariser-Parr-Pople) model in honour of these three authors. Thinking of the pyridine example above, we still divide the 42 electrons into two groups, the 6 7r-electrons and the 36 o--electrons. The spirit of the PPP model is that the cr-electrons and the atomic nuclei provide a potential for the TT-electrons. Attention focuses on the 7r-electrons. [Pg.137]

Various chiral dipolarophiles have been used in the asymmetric synthesis of hexahydro-isoxazolo[2,3- ]pyridines. Examples include // / -2-methylcnc-l, 3-dithiolane 1,3-dioxide 83 <1998JOC3481>, chiral vinyl sulfoxide 85 <1997TA109>, or chiral dioxolanes <2001TA1747> (Scheme 27). [Pg.432]

The arylation of support-bound arenes has mainly been performed using the Suzuki and Stille coupling reactions. Both reactions proceed smoothly with arenes and het-eroarenes such as furans, thiophenes, or pyridines. Examples of the arylation of het-eroarenes are presented in Chapter 15. [Pg.197]

Alkaloid. A class of nitrogen-containing organic compounds, usually derived from the nitrogen-containing ring compounds, such as pyridine. Examples of alkaloids include morphine, nicotine, codeine, cocaine, and caffeine. [Pg.643]

By the action of thionyl chloride upon the alcohol alone or mixed with pyridine (to absorb the hydrogen chloride formed in the reaction), for example ... [Pg.270]

The dichlorides of aliphatic glycols are obtained by reaction with thionyl chloride in the presence of a small quantity of pyridine, for example ... [Pg.270]

This is an example of the acid chloride - pyridine - acid method referred to in the theoretical section. [Pg.375]

Bromination of fatty acids in the a-position can be effected quite readily in the presence of phosphorus trichloride, red phosphorus or pyridine as catalysts or halogen carriers with acetic acid, the addition of acetic anhydride (to ensure the absence of water) improves the yield and facilitates the bromination. Examples are —... [Pg.427]

This preparation is another example of the condensation of an aldehyde with malonic acid and pyridine to 3neld ultimately an ap-unsaturated acid (Doebner reaction). It is included here because, unlike the acids prepared from many of the lower aUphatic aldehydes, the product consists largely (about 95 per cent.) of the ap-isomeride and only about 5 per cent, of the PY-isomeride is present ... [Pg.465]

The presence of certain substituents e.g., the amino group) may markedly affect the solubibty and other properties of the sulphonic acid or carboxylic acid. Thus such sulphonic acids as the aminobenzenesul-phonic acids, pyridine- and quinoline-sulphonic acids exist in the form of inner salts or zwitter-ions that result from the interaction of the basic amino group and the acidic sulphonic acid. Sulphanilic acid, for example, is more accurately represented by formula (I) than by formula (II) ... [Pg.1049]

We shall describe a specific synthetic example for each protective group given above. Regiosdective proteaion is generally only possible if there are hydroxyl groups of different sterical hindrance (prim < sec < tert equatorial < axial). Acetylation has usually been effected with acetic anhydride. The acetylation of less reactive hydroxyl groups is catalyzed by DMAP (see p.l44f.). Acetates are stable toward oxidation with chromium trioxide in pyridine and have been used, for example, for protection of steroids (H.J.E. Loewenthal, 1959), carbohydrates (M.L. Wolfrom, 1963 J.M. Williams, 1967), and nucleosides (A.M. Micbelson, 1963). The most common deacetylation procedures are ammonolysis with NH in CH OH and methanolysis with KjCO, or sodium methoxide. [Pg.158]

The pyridine-like nitrogen of the 2H-pyrrol-2-yiidene unit tends to withdraw electrons from the conjugated system and deactivates it in reactions with electrophiles. The add-catalyzed condensations described above for pyrroles and dipyrromethanes therefore do not occur with dipyrromethenes. Vilsmeier formylation, for example, is only successful with pyrroles and dipyrromethanes but not with dipyrromethenes. [Pg.255]

The cross-coupling of aromatic and heteroaromatic rings has been carried out extensively[555]. Tin compounds of heterocycles such as oxazo-lines[556,557], thiophene[558,559], furans[558], pyridines[558], and seleno-phenes [560] can be coupled with aryl halides. The syntheses of the phenylo.xazoline 691[552], dithiophenopyridine 692[56l] and 3-(2-pyridyl)qui-noline 693[562] are typical examples. [Pg.229]

For example, when N-ethylrhodanine is condensed with (quino)ine-4)(4-methylthiazole-2)trimethine cyanine or (pyridine-2)(4-methylthia-zole-2)trimethine cyanine, the yields obtained for neutrothiazolo-dimethine dye are 25 and 75%, respectively (53). [Pg.62]

Likewise, quantum mechanical calculation succeeds in giving a theoretical explanation of some facts that the resonance theory could not explain, for example, why bis(pyridine-2)monomethine cyanine and bis(pyridine-4)monomethine cyanine possess the same lowest energy transition contrary to the 2,2 - and 2,4 -quinoline monomethine dyes, together with a molecular coefficient extinction lower than that of the 4,4 -quinoline dye (11). Calculation shows also that there is no theoretical reason for observing a relationship between and pK in a large series of dyes with different nuclei as it has been postulated, even if limited observations and calculations in short homogeneous series could lead to this conclusion (105). [Pg.73]

The conversion of esters to hydrazides and of hydrazides to the sulfonyl derivatives occurs in good yield in the McFadyen-Stevens synthesis, but the decomposition of sulfonyl derivatives gives low yields of the desired products, for example, thiazole hydrazide (28) with 10% excess of PhSOjCl in pyridine gave a 75% yield of l-phenylsulfonyl-2-(4-methyl-5-thiazo ecarbonyl)hydrazine (29) (66). The Newman-Caflish modification of the McFadyen-Stevens synthesis gave 37% 4-methyl-5-thiazole-carboxaldehyde (30) (Scheme 27). [Pg.533]

The higher reactivity of 2-halogenothiazoles with respect to halogenopyridines can be related to the different aromaticity of the two systems, less for thiazole than for pyridine, for example, the relatively stronger fixation of the tt bond in the thiazole than in the case of pyridine. As the data reported in Table V-1 (footnote a) indicates, the free thiophenol is more reactive than the thiolate anion toward the 2-halogenothiazoles. This fact should be considered when one prepares the thiazolyl sulfides. [Pg.568]

Heterocyclic aromatic compounds can be polycyclic as well A benzene ring and a pyridine ring for example can share a common side m two different ways One way gives a compound called quinoline the other gives isoquinoline... [Pg.460]

Acid anhydrides react with alcohols to form esters The reaction may be carried out in the presence of pyridine or it may be catalyzed by acids In the example shown only one acyl group of acetic anhydride becomes incorporated into the ester the other becomes the ac yl group of an acetic acid molecule... [Pg.843]


See other pages where Pyridines, example is mentioned: [Pg.184]    [Pg.463]    [Pg.184]    [Pg.243]    [Pg.243]    [Pg.46]    [Pg.243]    [Pg.365]    [Pg.520]    [Pg.215]    [Pg.135]    [Pg.236]    [Pg.184]    [Pg.184]    [Pg.463]    [Pg.184]    [Pg.243]    [Pg.243]    [Pg.46]    [Pg.243]    [Pg.365]    [Pg.520]    [Pg.215]    [Pg.135]    [Pg.236]    [Pg.184]    [Pg.42]    [Pg.202]    [Pg.584]    [Pg.727]    [Pg.1135]    [Pg.196]    [Pg.533]    [Pg.711]    [Pg.175]    [Pg.161]    [Pg.65]    [Pg.109]    [Pg.462]   
See also in sourсe #XX -- [ Pg.400 ]




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