Pyrazine medicinal applications

In medicinal applications, l,2,3,4-tetrahydropyrazino[l,2-alindoles were of interest as high-affinity selective imidazoline receptor ligands <04BMCL1003>, 3,4-dihydro-l//-pyrido[2,3-l ]-pyrazin-2-ones as corticotropin-releasing factor-1 (CRF 1) receptor antagonists <04JMC5783>,... 

Scarcely a single issue of Chemical Abstracts is published without reference to medicinal compounds containing the pyrazine or quinoxaline ring in some form, and hence it is impractical to list all applications of pyrazines, quinoxalines and phenazines. Some of the more important applications and natural products, particularly the more recent developments, are mentioned in this Section. 

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