Putative promoter

Fig. 5. Comparison of putative promoter elements in pgaW promoters from different Aspergilli. The sequence of strain RH53344 was taken from Ruttkowski et al.

Table 8.1 Proven and putative promoters and inhibitors of nucleation of cholesterol microcrystals in gallbladder bile.

Popendikyte V, Laurinavicius A, Paterson AD, Macciardi F, Kennedy JL, Petronis A. DNA methylation at the putative promoter region of the human dopamine D2 receptor gene. Neuroreport 1999 10 1249-1255. 

While the specific location of cis- and -trans-acting sequences regulating DTNPB1 gene expression remain to be established, one of the former maybe in the first putative promoter. In that location, Pedrosa et al. (2009) identified a likely regulatory sequence between nucleotides 15,770,998 and 15,771,876 on the minus strand of chromosome 6p. That sequence is of special interest, because it contains a SNP location associated with schizophrenia in multiple studies (i.e., rs2619538 see Table 2.2-14). 

Two regions of the GnT V promoter have been identified as positive regulatory elements [200, 201]. Both regions contained an Ets consensus sequence and gel mobility shift experiments showed that both regions bound the Ets protein. Cotransfection of luciferase constructs controlled by either of the two putative promoter regions and an Ets expression plasmid showed stimulation of luciferase by the Ets product. 

It is important to note that email marketing is no longer about email blcists. Email blasts are those old batch-and-blast spammy emails that marketers used to send to leads. Those just don t work anymore, particularly with new email advancements like the new tabbed inbox in Gmail that automatically puts promotional emails in a separate tab from the user s primary messc es. Marketers have to work to get their email messages seen. 

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