SNPs in PXRs Promoter and Intron 1 Affect Putative HNF Binding Sites

10 SNPs IN PXR s PROMOTER AND INTRON 1 AFFECT PUTATIVE HNF BINDING SITES 

The results from several studies suggest that HNF3(3 (also known as fork head transcription factor FoxA2) and other hepatic transcription factors such as HNF4 and HNF1 may influence transcriptional activity of the PXR promoter and that SNPs 

FIGURE 9.4 PXR promoter and intron 1 SNPs associated with various traits in liver and intestine. 

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