Public health goals

Maximum Contaminant Level Goal (MCLG) - The level of a contaminant in drinking water below which there is no known or expected risk to health. MCLGs allow for a margin of safety and are non-enforceable public health goals. 

California EPA, Public Health Goal for Methyl Tert Butyl Ether (MTBE) in Drinking Water, Office of Environmental Health Hazard Assessment, Sacramento, CA. Available at http //www.oehha.ca.gov/ water/phg/allphgs.html, 1999. 

Several NCI scientists began, in the early 1960s, to think there was a need for standardized protocols. They thought that one extremely important public health goal was simply to identify, using well-understood animal models, chemicals that had the capacity to induce malignancies. The regulatory and public health community could then decide how and to what extent human exposure to those substances should be controlled. 

Howd RA, Brown JP, Morry DW, et al. 2000. Development of California public health goals (PHGs) for chemicals in drinking water. J Appl Toxicol 20 365-380... 

Covington TR, Gentry PR, Van Landingham CB, Andersen ME, Kester JE, Clewell HJ. 2007. The use of Markov chain Monte Carlo uncertainty analysis to support a public health goal for perchloroethylene. Regul Toxicol Pharmacol 47 1-18. 

Pheromones Biochemicals used to disrupt the mating behavior of insects PHG Public health goal... 

Currently, there are no US federal or international occupational or environmental standards for ammonium perchlorate. California has a public health goal (PHG) for perchlorate of 6 ppb. 

States in the United States may develop or adopt drinking water standards and guidance that is equal to or more restrictive than criteria prepared under the Federal SDWA. For example, California develops Public Health Goals (PHGs). 

Maximum contaminant level goals (MCLGs) are nonenforceable public health goals. MCLGs are set at levels where there is no known or expected risk of adverse effects. They do not consider detection limits or available treatment technology to reduce levels of constituents and may be set at levels that cannot be achieved in certain public water systems. Once the... 

The Office of Environmental Health Hazard Assessment of the California Environmental Protection Agency has established a public health goal of 10 ppb for vinylidene chloride in drinking water. This... 

Office of Environmental Health Hazard Assessment (OEHHA) (1999) Public Health Goal for 1,1-Dichloro-... 

EPA values from Integrated Risk Information System (IRIS) (2008), OEHHA values (rounded to 1 significant figure) from Public Health Goal documents, available at http //www.oehha.ca.gov/water/phg/allphgs.html. 

Because the risk for atherosclerotic disease is directly proportional to the plasma levels of LDL cholesterol and inversely proportional to those of HDL cholesterol, a major public health goal has been to lower LDL and raise HDL cholesterol levels. The most successful drug Interventions to date have been aimed at reducing plasma LDL. The steady-state levels of plasma LDL are determined by the relative rates of LDL formation and LDL removal or clearance. LDL receptors, especially those expressed In the liver, play a major role in clearing LDL from the plasma. The liver Is key In cholesterol regulation not only because It Is the site of about 70 percent of the body s LDL receptors, but also because it is the site where unesterified cholesterol and Its bile acid... 

Thomas DH, Rohrer JS, Jackson PE, Pak T and Scott JN (2002) Determination of hexavalent chromium at the level of the California Public Health Goal by ion chromatography. J Chromatogr A 956 255-259. 

The Committee noted that the reduction of dietary AFT exposure is an important public health goal, particularly in populations that consume high levels of any potentially AFT-contaminated food. 

Regarding dried figs, the Committee concluded that whatever the hypothetical ML scenario applied (no ML, 4,8,10,15 or20 pg/kg), there would be no impact on the overall dietary exposure to AFL. The Committee noted that the reduction of dietary AFL exposure Is an Important public health goal, particularly in populations that consume high levels of any potentially AFL-contaminated food. The previous PTWI of 100 ng/kg bw was retained. 

Figure 2 Ion chromatograms of chromate in drinking waters (A) unspiked sample, (B) sample spiked with 0.2pgl Cr(VI). (Reprinted with permission from Thomas DH, Rohrer JS, Jackson PE, Pak T, and Scott JN (2002) Determination of hexavalent chromium at the level of California public health goal by ion chromatography. Journal of Chromatography A 956 255-259 Elsevier.)...

OEHHA (2001) Public health goal for chemicals in drinking water uranium. Prepared by the Office of Environmental Health Hazard Assessment, California Environmental Protection Agency, CA, USA, August 2001. 

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