Pseudomonas roseus fluorescens

Pseudomonas roseus fluorescens (288), Pseudomonas GH (324) and Erwinia rhapontici (113) produce pro-ferrorosamine A (81), also named pyrimine, which forms a red (Fe )Lig3 complex. Under acidic conditions, an open form of pro-ferrorosamine A prevails, which cannot bind Fe " (Cliart 5). Pro-ferrorosamine B is probably an artifact produced by condensation of pro-ferrorosamine A with CHO-COOH. Pro-ferrorosamine A is essential for iron uptake by Pseudomonas (367) and for the pathogenicity of Erwinia (114). 

Proferrorosamine A.—The Pseudomonas roseus fluorescens metabolite pro-ferrorosamine A (48) derives efficiently from picolinic acid (49). A further result" is that L-[l/- C]lysine was also well incorporated and again the activity was confined to the picolinic acid moiety of (48). 

No known biological activity. Isolated from Pseudomonas GH fermentation in yield of 1.0 g from 10 1 of medium. Also produced by B. roseus fluorescens. 

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