Pseudomonas pyocyaneus aeruginosa

Pyocyanine. 1 -Hydroxy-S-methylphenazini u m hydroxide inner salt. C,3HWNJ3 mol wt 210.23. C 74.27%, H 4.80%, N 13.32%, O 7.6]%. Produced by Pseudomonas aeruginosa (Ps. pyocyanea, Bacillus pyocyaneus). Isoln from broth cultures Wrede, Si rack. Z. Physiol Chem. 140, 1 (1924). Isoln from agar cultures Sohoental, Brit J, Exp Pathol. 22, 137 (1941). Synthesis by dimethyl sulfate meth-ylation of a -hydroxyphenazine and alkaline treatment of the resulting methosulfate Wrede, Strack, Z. Physio/, Chem. 181, 58 (1929) Ber. 62, 2051 (1929) Surrey, Org- Syn. 26, 86 (1946) coll, voL HI, 753 (1955). 

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