Pseudomonas incognita

In 1977, a Pseudomonad was isolated from soil by enrichment culture technique with linalool as the sole source of carbon and energy [36]. The bacterial strain was later identified as Pseudomonas incognita and given the name linalool strain . It was also capable of growing on geraniol, nerol and limonene. The biotransformation of geraniol by this... 

Fig. (7). Pathways of degradation of geraniol by Pseudomonas incognita (after [32])...

As mentioned before, a Pseudomonas incognita was isolated by enrichment technique on the monoterpene alcohol linalool that was also able to grow on geraniol, nerol and limonene [36]. The metabolism of limonene by this bacterium was also investigated [37]. After fermentation the medium yielded as main product a crystallic acid, perillic acid, together with unmetabolised limonene, and some oxygenated compounds dihydrocarvone, carvone, carveol, p-menth-8-en-1 -ol-2-one, p-menth-8-ene-1,2-diol or p-menth-1 -ene-6,9-diol (structure not fully elucidated) and finally / -isopropenyl pimelic acid. 

Rama-Devi, J. and Battacharyya, P.K. 1977. Microbial transformation of terpenes Part XXIV. Pathways of degradation of geraniol, nerol and limonene by Pseudomonas incognita (linalool strain). Indian J. Biochem. Biophys. 14 359-363. 

Limonene is metabolized predominantly to (+)-perillic acid (103 R = CO2H) by Pseudomonas incognita, presumably via C-7 hydroxylation, which has also been reported in the conversion of a-terpineol into 7-hydroxy-a-terpineol in further work (see Vol. 8, p. 26) on callus cultures of Nicotiana tabacum and is also presumed to be involved to account for the isolation of oleuropeic acid (140)... 

Ropp JD, Gunsalus IC, Sligar SG (1993) Cloning and expression of a member of a new cytochrome P-450 family cytochrome p-4501in (CYPl 11) from Pseudomonas incognita. JBacteriol 175 6028-6037... 

FIGURE 19.7 Metabolism of geraniol (271) hy Pseudomonas incognita. (Modi ed from Madyastha, K.M., Proc. Indian Acad. Sci. Chem. Sci), 93, 677, 1984.)... 

FIGURE 19.17 Biotransformation of linalool (206) by Pseudomonas incognita (Madyastha et al., 1977) and Streptomyces albus NRRL B1865. (Modi ed from David, L. and Veschambre, H., Tetrahadron Lett., 25, 543, 1984.)... 

Rama Devi, J., S.G. Bhat, and P.K. Bhattacharyya, 1977. Microbiological transformations of terpenes. Part XXV. Enzymes involved in the degradation of linalool in the Pseudomonas incognita, linalool strain. Indian . Biochem. Biophys., 15 323-327. 

Pseudomonas incognita Linalool-10-methyl-hydroxlase Linalool-8-methyl-hydroxlase... 

---