Pseudomonas aeruginosa lower respiratory tract infection

A 16-year-old girl, a cystic fibrosis patient, is diagnosed with a ciprofloxacin-resistant Pseudomonas aeruginosa lower respiratory tract infection. 

Lower respiratory tract infections, including pneumonia and lung abscess caused by Haemophilus influenzae, Klebsiella sp. including K. pneumoniae, Proteus mirabilis. Pseudomonas sp. including P. aeruginosa, E. coli, and Bacteroides sp. including B. fragilis... 

CF is an aufosomal recessive disease affecting more than 50,000 individuals worldwide, primarily, although not exclusively, white individuals. The disease affects epithelium-lined organs, such as the respiratory and intestinal tracts, of which the former are the site of major morbidity and mortality. Recurrent chest infections and colonization of the lower airways with organisms such as Staphylococcus aureus and Pseudomonas aeruginosa progress to subsequent bronchiectasis and finally respiratory ilure, the most common cause of death. 

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