Pseudoligand

Young, P., and Gautel, M. (2000). The interaction of titin and alpha-actinin is controlled by a phospholipid-regulated intramolecular pseudoligand mechanism. EMBOJ. 19, 6331-6340. 

Chi, Y.I., Yokota, H. and Kim, S.H. (1997). Apo structure of the ligand-binding domain of aspartate receptor from Escherichia coli and its comparison with ligand-bound or pseudoligand-bound structures. FEES Lett. 414, 327-332. 

Figure 12 illustrates that while the Cu7N,N,N, N", N"-pentamethyldiethylenetriamine (PMDETA) complex is active, it disproportionates in aqueous ATRP. On the other hand, ligands such as bpy, HMTETA, and TPMA can be used in aqueous media, although with rather different activities. If necessary, catalyst disproportionation in water can be suppressed by using an appropriate cosolvent or by addition of a pseudoligand that will stabilize Cu versus Cu , such as pyridine, which allows... 

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