Protein targeting overview

Pfeffer, S. R., and J. E. Rothman, Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi. Ann. Rev. Biochem. 56 829, 1987. An excellent overview of the major features of protein targeting in eukaryotic cells. 

ATP -h protein tyrosine <322-324> (some kinases are able to phosphory-late both serine/threonine and tyrosine, <322> [667] specificity, <324> [682] structure-fmction relationship, <324> [683] in vitro specificity, <324> [689] <322> overview of the best studied protein targets of src kinases, functions [708]) [667-669, 680, 682, 683, 685, 688-690, 692, 708] ADP -I- protein tyrosine phosphate... 

Figure 3 provides a very general overview of transcriptional activation in response to a PPAR ligand. Fig. 3a shows the schematic representation of a PPAR target gene in the absence of PPAR ligand. Co-repressor proteins bound to both unliganded PPAR and RXR... 

Combi R, Dalpra L, Tenchini ML, Ferini-Strambi L (2004) Autosomal dominant nocturnal frontal lobe epilepsy A critical overview, J Neurol 251 923-934 Connolly J, Boulter J, Heinemann SF (1992) Alpha 4-2 beta 2 and other nicotinic acetylcholine receptor subtypes as targets of psychoactive and addictive drugs, Br J Pharmacol 105 657-666 Conti-Tronconi BM, Dunn SM, Barnard EA, DoUy JO, Lai FA, Ray N, Raftery MA (1985) Brain and muscle nicotinic acetylcholine receptors are different but homologous proteins, Proc Natl Acad Sci U S A 82 5208-5212... 

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