Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Protein homology detection

Soding J. Protein homology detection by HMM-HMM comparison. Bioinformatics 2005 21 951-960. [Pg.55]

Saigo, H., Vert, J.-R, Ueda, N., Akutsu, T. Protein homology detection using string alignment kernels. Bioinformatics 2004,20,1682-9. [Pg.61]

Henikoff, S., and Henikoff, J. G. (2000). Protein family-based methods for homology detection and analysis. In Bioinformatics, A Practical Approach. (D. Higgins, and W. Taylor, eds.), IRL Press, (In press). [Pg.96]

Key words Helicobacter pylori, Proteins, Remote homology detection, Function assignment... [Pg.155]

In some proteins, only a part of the H. pylori protein is assigned a functional domain by Pfam and the rest of the protein is not assigned any function. Remote homology detection methods employed in the current analysis have established relationships between these unassigned regions and Pfam domain families. [Pg.171]

Karplus, K., Barrett, C., Hughey, R. (1998) Hidden Markov models for detecting remote protein homologies,... [Pg.75]

Ruv protein homology has not yet been detected in eukaryotic cells, but much of the mechanism appears to be similar to that of E. coli. For example, the RAD51 protein of human cells and yeast has a strandpairing activity similar to that of RecA. [Pg.1903]

Jaakkola, T, Diekhans, M., Haussler, D. A discriminative framework for detecting remote protein homologies. J. Gomput. Biol. 2000, 7, 95-114. [Pg.61]

Hou, Y., Hsu, W, Lee, M.L., Bystroff, C. Remote homolog detection using local sequence-structure correlations. Proteins Struct., Funct., Bioinf. 2004, 57, 518-30. [Pg.61]

Fig. 1. Diagram illustrates the principle of Src homology-2 (SH2) domain array for genome-profiling tyrosine phosphorylation. There are three basic steps 1. SH2 domains are spotted on Polyvinylidene fluoride (PVDF) membrane 2. Cell lysate is incubated with array 3. The phosphorylated proteins are detected with phosphotyrosine antibody. Fig. 1. Diagram illustrates the principle of Src homology-2 (SH2) domain array for genome-profiling tyrosine phosphorylation. There are three basic steps 1. SH2 domains are spotted on Polyvinylidene fluoride (PVDF) membrane 2. Cell lysate is incubated with array 3. The phosphorylated proteins are detected with phosphotyrosine antibody.
Another important application of clustering in life sciences is molecular, particularly protein, structures comparison. Most of the comparative analysis involves the direct alignment and superimposition of stmctures in a three-dimensional space (Xiong, 2006). According to (Xiong, 2006). The stmcture comparison is one of the fundamental techniques in protein stmcture analysis for three reasons (a) it can detect remote protein homologs, since stmctural comparison can reveal distant evolutionary relationships between proteins (b) it is a prerequisite for protein stmctural classification and (c) comparison of theoretically known stmctures with experimentally predicted ones is a critical procedure in the evaluation of protein stmcture prediction methods. [Pg.99]


See other pages where Protein homology detection is mentioned: [Pg.61]    [Pg.387]    [Pg.61]    [Pg.387]    [Pg.330]    [Pg.210]    [Pg.315]    [Pg.155]    [Pg.156]    [Pg.158]    [Pg.164]    [Pg.171]    [Pg.117]    [Pg.102]    [Pg.5562]    [Pg.123]    [Pg.447]    [Pg.535]    [Pg.580]    [Pg.590]    [Pg.11]    [Pg.253]    [Pg.258]    [Pg.426]    [Pg.393]    [Pg.5561]    [Pg.89]    [Pg.43]    [Pg.292]    [Pg.162]    [Pg.637]    [Pg.420]    [Pg.258]    [Pg.258]    [Pg.338]    [Pg.280]   
See also in sourсe #XX -- [ Pg.387 ]




SEARCH



Homologous proteins

Homology detection

Protein detection

Protein homologs

Protein homology

© 2024 chempedia.info