2- propylphosphonic acid

Challenge Water (tap) PEGs + O-Propyl propylphosphonic acid 2.B.4... 

Liquid Chromatography Methylphosphonic Acid Mass Spectrometry Methyl-A-tert(butyldimethylsilyl) trifluoroacetamide Nuclear Magnetic Resonance Propylphosphonic Acid Recommended Operating Procedure... 

Fosfomycin, the (IR,IS) (-)-l,2-cpoxy propylphosphonic acid, formerly called phosphonomycin, is a low-molecular-weight antibiotic of unusual structure that was originally isolated in 1969 from used culture medium of Streptomyces fradiae (Figure 4.l),i. 86-i88 yjjg structure was established by... 

Arbuzov, B.A., Vinogradova, V.S., and Polezhaeva. N.A., Product of reaction of diethyl sodiophosphite with bromoacetone, Dokl. Akad. Nauk SSSR, 111, 107, 1956 Chem. Abstr, 51, 8001g, 1957. Abramov, V.S., and Kapustina, A.S., Esters of a-hydroxy-P-chloro-isopropylphosphonic acid and 1,2-epoxy-2-propylphosphonic acid, Dokl. Akad. Nauk SSSR, 111, 1243, 1956 Chem. Abstr, 51, 9473g, 1957. 

Addition of ethyl 2-pyridylacetate to diethyl vinylphosphonate without solvent using EtONa as catalyst produces diethyl 3-(ethoxycarbonyl)-3-(2-pyridyl)propylphosphonate in 60% yield. Acid hydrolysis with 10 M HCl followed by decarboxylation of the product gives the 3-(2-pyridyl)propylphosphonic acid in 50% yield (Scheme 8.60). 

Maruszewska-Wieczorkowska, E., and Michalski, J., Alkyl and alkenyl pyridines. Part 7. 3-(2 -Pyridyl) propylphosphonic acid, Rocz. Chem., 37, 1315, 1963. 

The rather low yields of the aminophosphonic acids can be fairly substantially improved over those reported by Kabachnik and Medved if anhydrons ammonia and the aldehyde are premixed in alcohol solution. Using this procedure, a few amino-substituted phosphonic acids are prepared a-aminobenzylphosphonic acid (benzaldehyde, dibutyl H-phosphonate, solution of dry ammonia in absolute ethyl alcohol) a-amino-propylphosphonic acid propionaldehyde, diethyl H-phosphonate, and a solntion of dry ammonia in absolute ethyl alcohol) p-methoxybenzyl-a-aminophosphonic acid (p-hydroxybenzaldehyde, diethyl H-phosphonate, and solution of dry ammonia in absolute ethyl alcohol). 

Fig. 1 HPLC-ESP MS reconstructed (total) ion chromatogram from a standard mixture of alkyl phosphonic acids at a concentration of 1 p-g/ml each 1) methylphosphonic acid (MPA) 2) ethylphosphonic acid (EPA) 3) methyl ethylphosphonic acid (MEPA) 4) ethyl methylphosphonic acid (EMPA) 5) ra-propylphosphonic acid (nPrPA) 6) ethyl ethylphosphonic acid (EEAP) 7) isopropyl methylphosphonic acid (iPrMPA) 8) n-propyl methylphosphonic acid (nPrMPA) 9) isopropyl ethylphosphonic acid (iPrEPA) 10) n-propyl ethylphosphonic acid (nPrEPA) 11) isohutyl methylphosphonic acid (iBuMPA) 12) cyclohexyl methylphosphonic acid (CHMPA) 13) pinacolyl methylphosphonic acid (PinMPA).

Besides LiBOB, other additives have been reported to protect the high voltage cathode and mitigate electrolyte decomposition, including LiDFOB [162], succinic anhydride [66, 122], 1,3-propane sultone [66], tris(hexafluoro- o-propyl) phosphate [127], tris(pentafluorophenyl) phosphine [156], 3-hexylthiophene [3], 1,3-propanediolcyclic sulfate [41], dimethylacetamide [13], triethyl(2-methoxyethyl) phosphonium bis(trifluoromethylsulfonyl)imide [13], glutaric anhydride [16], 4-(trifluoromethyl)-benzonitrile [55], and 1-propylphosphonic acid cyclic anhydride [ 160]. The stmctures of the additives that are not listed in the previous text are shown in Fig. 8. 

Glutaric anhydride 4-(Trifluoromethyl)-benzonitrile 1-Propylphosphonic acid... 

Yan G, Li X, Wang Z, Guo H, Xiong X (2014) Beneficial effects of 1-propylphosphonic acid cyclic anhydride as an electrol5fie additive on the electrochemical properties of LrNio.sMni 5O4 cathode material. J Power Sources 263 231-238. doi 10.1016/j.jpowsour. 2014.04.060... 

The cycling performance of graphite/LiNio.5Coo.2Mno.302 battery in the electrolyte with a different content from 0% to 2.0% of 1-propylphosphonic acid cyclic anhydride, cf. Figure 2.16, has been... 

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