Propyl Protein salts

This conception works out as shown in Scheme 10 CTP 23 formed by the above described sequence is directly consumed by -acetyl neuraminic acid 26 under the catalytic influence of cytidine-5 -monophosphosialate synthase (E.C. 2.7.7.43). This enzyme is isolated from calf brain by ammonium sulfate precipitation (2 5) and subsequent affinity chromatography. The stationary phase consists of CNBr-activated Sepharose 4B reacted with p-[3-(2-amino ethylthio)propyl]-iV-acetyl neuraminic acid 27, which is synthesized by radiating a mixture of the allyl glycoside and cysteamine to achieve radical C-S bond formation (24), The behavior of methyl p-N-acetyl-neuraminic acid as an inhibitor is in accordance with Zbiral s findings (25), where the methyl a-glycoside has been shown to compete with the native substrate for the enzyme, and thus 27 is recommended to be an ideally suited ligand (Scheme 9). A typical analytical run is shown in Scheme 9. Due to elution of the protein fraction by a salt gradient, the transfer to a preparative scale is rather difEcult denaturation occurs and thus a drop in activity down to 6% is observed. 

With hydrophobic interaction chromatography (HIC), hydrophobic proteins interact with slightly hydrophobic surfaces (propyl, ether, phenyl) at high salt concentrations. For elution, a salt gradient from high to low salt concentrations... 

Manuf./Distrib. Somerset Cosmetic Co, Variati Trade Names Containing Foamquat CHP Linoleamidopropyl hydroxypropyl dimonium hydrolyzed oat protein Uses Conditioner in cosmetics Manuf./Distrib. McIntyre UK Trade Names Containing Maokpro LOP Linoleamidopropyl PG-dimonium chloride phosphate Synonyms Linoleamidopropyl phosphatidyl PG-dimonium chloride 1-Propanamin-ium,2,3-dihydroxy-N,N-dimethyl-N-[3-(1-oxo-9,12-octadecadienylamino) propyl]-, 3-phosphate triester, trichloride Ciassification Quaternary ammonium salt tonic Nature Cationic... 

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