3- propiophenone oxime

C,3H,9N03 2-Hydroxy-4-n-butoxy-propiophenone oxime Spectrophotometric Fe 44... 

Oxo-l,2,4-oxadiazepines (507) have been prepared by the reaction of hydroxyurea with some a, (3-unsaturated ketones (75TL2979). sy -to-(Benzylamino)propiophenone oximes (508) react with phosgene to give the 7-oxo-l,2,6-oxadiazepines (509) (75CB3387), and with formaldehyde to give (510) (80CB3373). 

The effect of the KOH content of the reaction mixture upon the yield of 3-methyl-2-phenyl-l-vinylpyrrole from propiophenone oxime and acetylene (100°C, 3 hr) is expressed as follows (78ZOR1733)... 

The only example of this system that has been prepared is (139). Refluxing jS-arylamino-propiophenone oximes (138) with formaldehyde in ethanol resulted in the condensation with ring closure to give the tetrahydro-l,2,6-oxadiazepines (139) in good yields (Equation (5)) <91MI 914-03). 

S-[(Chloroacetyl)amino]propiophenone oximes cyclocondense on treatment with alkali to form the 3-aryl-l,2,6-oxadiazocin-7-ones (32), as shown in Equation (5) <84LAI696>. 

The E or Z nomenclature can also replace the older S)m-anti terminology. Compound 51 has been called sj/n-propiophenone oxime because the OH and the phenyl are on the same side of the double bond, while 52 has been called the anti isomer because these two larger groups are on opposite sides. The distinction between syn and anti depends on the size or complexity of the substituents, and that may not always be unambiguous. Moreover, many authors reserve the terms syn and anti to describe the stereochemical pathway of a reaction, not the stereochemistry of molecules. With the E or Z system, 51 is unambiguously the Z isomer, while 52 is the E oxime. 

More recently, the same group reported another novel procedure for the synthesis of pyridines by cyclization of ketoxime acetates with ruthenium as the catalyst (Scheme 3.46) [95]. Here, a methyl carbon on DMF performed as a source of a one carbon synthon. For different propiophenone oxime carboxylates tested, such as propionate, tert-butyrate, and benzoate, showed similar reactivity as the corresponding acetate derivative. Only a trace of product was observed with pentafluorobenzoate. 

Methoxy-beazylallophanat 61440. oi.IIitiro-4-methozy-propiophenon-oxim... 

Dlitboxy-propiophenonoxini 8, 280. S-Ifethoxy- propyloxy-propiophenon-oxim 8, 280. 

Athylainmo-benzaldazim 14. 36. 14Amiiio-piopiophenoii zim 14 II37. 4-Anuno.propiophenon.oxim 14 1 375. 2-Amino-A5-diine(hyl.beazaldehyd.ozim... 

D, Miscellaneous - Various compounds reported this year are claimed to possess analgesic potency equal to or better than codeine. The, basic propiophenone oxime, U3VP E 142 (23) has morphine-level activity with no respiratory depression, suppression of withdrawal syndrome capacity or nalorphine interaction. Related compounds (24), of similar potency, were reported at the Spring A.G.3. meeting. The pharmacology of aletamine... 

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