3- propionyl hydrazide

BODIPY 530/550 C hydrazide is 4,4-difluoro-5,7-diphenyl-4-bora-3a,4a-diaza-s-indacene-3-propionyl hydrazide, a derivative of the basic BODIPY structure that contains two phenyl rings off the No. 5 and 7 carbon atoms and a propionic acid hydrazide group on the No. 3 carbon... 

BODIPY 530/550 C3 Hydrazide 4,4-difluoro-5,7-diphenyl-4-bora-3a,4a-diaza-s-indacene-3-propionyl hydrazide MW 430... 

Metal deactivators N,N -bis(3-(3,5-di-tert-butyI-4-hydroxyphenyl)propionyl) hydrazide... 

BODIPY 593/503 C3 hydrazide is 4,4-difluoro-l,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene-8-propionyl hydrazide (Molecular Probes). Unlike BODIPY 530/550 C3 hydrazide, this BODIPY derivative contains substituents that shift to lower wavelengths the spectral characteristics of its fluorescent properties. The molecule is highly reactive toward aldehyde-containing compounds, including glycoproteins that have been oxidized with sodium periodate to create the requisite groups (Fig. 230). 

DNA-conjugated polymers were prepared from polyallylamine or polyacrylic acid (PAA) modified with ssDNA as a probe, and thioctic acid (TA) or 3-(pyridyldithio)propionyl hydrazide (PDPH) for self-assembled immobilization. The oligonucleotides sequences of the probes and of the fully matched and unmatched DNAs were S -TCC-TCT-TCA-TCC-TGC-TGC-TAT-GCC-TCA-TCT-T-R, 5 -AGA-TGA-GGC-ATA-GCA-GCA-GGA-TGA-AGA-GGA-3, ... 

We have studied the preparation of 5-ethyi-1,3,4-oxa-diazoiinone (VII) by phosgenation of propionyl hydrazide as depicted in scheme 203 (Ref. 255). 

Ethyl-1,3,4-oxadiazolinone (VIII), prepared by phosgenation of propionyl hydrazide as already described in section 3-4-2, is a key building block for the synthesis for the synthesis of 1,2,4-triazol-3-ones type antidepressants (Ref 255). 

Triazolone 167, a useful building block for APIs such as Nefazodone or Eto-peridone [52942-31-1] 168, an antidepressant, can be obtained from 5-ethyl-l,3,4-oxadiazolinone 165, which, in turn, is prepared by phosgenation of propionyl hydrazide 164 without the need for the highly toxic ethyl isocyanate [127]. 

Therefore, we developed a drug delivery vehicle (DDV) comprising the nontoxic recombinant heavy chain of BoNT-A coupled to a 10-kDa amino dextran via the heterobifunctional linker 3-(2-pyridylthio)-propionyl hydrazide. The heavy chain served to target botulinum neurotoxin-sensitive cells and promote internalization of the complex, while the dextran served as a platform to deliver model therapeutic molecules to the targeted cells. 

Pyridazines were obtained also by photolysis of 1-phenyl-l-vinyl azide in the presence of iron pentacarbonyl (3,6-di-phenylpyridazine was obtained in 1.1% yield) (78HCA589) or by thermal decomposition of an allenic hydrazonate (81JA7011). Acetylenic hydrazides can be transformed into pyridazines [84BSF(2)129], and thermal cyclization of dialkali metal salts of cu-hydroxyketone tosylhydrazones afforded pyridazines in moderate yield (85TL655). Propionyl phenylhydrazine, after reaction with 4-bromobutyronitrile, converts into a pyridazine (87SC1253). 

Another example of intramolecular CT complex formation is provided by trans-4-dimethvlamino-4 -(1-oxobutvl)stilbene Solvent effects on the spectrum give a value of 22D for the excited state dipole moment. The effect of electric field on the fluorescence of 4-(9-anthry1)-N.N.-2.3,5,G-hexamethy1-aniline shows this compound forms an excited state whose dipole moment does not change with solvent . Chiral discrimination in exciplex formation between 1-dipyrenylamine and chiral amines is very weak . In the probe molecule PRODAN (6-propionyl)-2-(dimethylamino)—naphthalene the initially formed excited state converts to a lower CT state as directly evidenced by time-resolved spectra in n-butanol. Rate constants for intramolecular electron transfer have been measured in both singlet and triplet states of covalently porphyrin-amide-quinone molecules . Intramolecular excimer formation occurs during the lifetime of the excited state of bis-(naphthalene)hydrazides which are used as photochemical deactivators of metals in polyethylene . ... 

N,N -8is(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionyl)-hydrazine. 2-(3-(3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl)-1-oxo-propyl)hydrazide Bis(3,5-di-tert-butyl-4-hydroxy-... 

Hydrazino compounds can react with carboxy compounds in aqueous medium to form hydrazide. For the reaction to proceed under mild conditions, N-ethyl-N -(3-dimethylaminopropyl) carbodiimide (EDC) is required as a condensing reagent. Fatty acids are determined with 2-nitrophenylhydrazine hydrochloride (NPH) by LC-UV detection. The detection limits for long chain fatty acids are 2.5-5 pmol per injection. As FL derivatization reagents, 6,7-dimethoxy-l-memyl-2( lH)-quinoxalinone-3-propionyl carboxylic... 

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