L,3-bis propane

Propane l,3-Bis-[4-chloro-phenyl]-2-bromo-3-fluoro-l-oxo-ElOa, 239 (En + HF/NBS)... 

Chlorides are inert. However, the reaction ofp-chlorobenzophenone (9) with a styrene derivative proceeds satisfactorily at 150 C by u.sing dippb [l,4-bis(-diisopropylphosphino)butane] as a ligand to give the stilbene derivative 10. However, dippp [l,3-bis(diisopropylphosphino)propane] is an ineffective ligand[13]. On the other hand, the coupling of chlorobenzene with styrene proceeds in the presence of Zn under base-free conditions to afford the cis-stilbene 11 as a main product with evolution of H . As the ligand, dippp is... 

Abbreviations acac, acetylacetonate Aik, alkyl AN, acetonitrile bpy, 2,2 -bipyridine Bu, butyl cod, 1,5- or 1,4-cyclooctadiene coe, cyclooctene cot, cyclooctatetraene Cp, cyclopentadienyl Cp, pentamethylcyclopenladienyl Cy, cyclohexyl dme, 1,2-dimethoxyethane dpe, bis(diphenyl-phosphino)ethane dppen, cis-l,2-bis(di[Atenylphosphino)ethylene dppm, bis(diphenylphosphino) methane dppp, l,3-bis(diphenylphosphino)propane eda,ethylenediamine Et,ethyl Hal,halide Hpz, pyrazole HPz, variously substituted pyrazoles Hpz, 3,5-dimethylpyrazole Me, methyl Mes, mesityl nbd, notboma-2,5-diene OBor, (lS)-endo-(-)-bomoxy Ph, phenyl phen, LlO-phenanthroline Pr, f opyl py, pyridine pz, pyrazolate Pz, variously substituted pyrazolates pz, 3,5-dimethylpyrazolate solv, solvent tfb, tetrafluorobenzo(5,6]bicyclo(2.2.2]octa-2,5,7-triene (tetrafluorobenzobanelene) THE, tetrahydrofuran tht, tetrahydrothicphene Tol, tolyl. 

The regioselective arylation of butyl vinyl ether was carried out by the same group, using Pd(OAc)2 as catalyst precursor and l,3-bis(diphenylphosphino)-propane (dppp) as the ligand, dissolved in [BMIM][Bp4] (Scheme 5.2-17) [90]. 

Ally 1(trialky 1)- and allyl(triaryl)stannanes react with aldehydes and electron-deficient ketones on heating to give homoallylic alcohols48, although rather high temperatures are required. 2-Methylene-l,3-bis(tributylstannyl)propane is somewhat more reactive49-50, as are allyltin halides, which can be used in the presence of water51. 

The stability of polyanhydrides composed of the diacids sebacic acid (SA), bis( -carboxyphenoxy)methane (CPM), l,3-bis(g-carboxyphe-noxy)propane (CPP), l,6-bis( -carboxyphenoxy)hexane (CPH), and phenylenedipropionic acid (PDP), in solid state and in organic solutions, was studied over a 1-year period. Aromatic polyanhydrides such as poly(CPM) and poly(CPH) maintained their original molecular weight for at least a year in both solid state and solution (20). 

Bidentate sulphoxides, such as 1,3-bis(methylsulphinyl)propane, l,4-bis(methyl-sulphinyl)butane and 1,2-bis(ethylsulphinyl)ethane, have been synthesized and employed as ligands toward Mn Co Ni Cu and Zn All metal ions are bound to the ligands via the oxygen of the sulphoxide groups and are six-coordinate, as shown in Scheme 20, with the exception of Cu, which is four-coordinate. 

Recently, Y. Yamamoto reported a palladium-catalyzed hydroalkoxylation of methylene cyclopropanes (Scheme 6-25) [105]. Curiously, the catalysis proceeds under very specific conditions, i.e. only a 1 2 mixture of [Pd(PPh3)4] and P(o-tolyl)3 leads to an active system. Other combinations using Pd(0 or II) precursors with P(o-tolyl)3 or l,3-bis(diphenylphosphino)propane, the use of [Pd(PPh3)4] without P(o-tolyl)3 or with other phosphine ligands were all inefficient for the hydroalkoxylation. The authors assumed a mechanism in which oxidative addition of the alcohol to a Pd(0) center yields a hydrido(alkoxo) complex which is subsequently involved in hydropal-ladation of methylenecyclopropane. 

FIGURE 6.32 Configurationally different spiro tetramers 44a and 44b formed by spiro tetramerization of l,3-bis(5-tocopheryl)propane (43) in a 15 1 ratio in agreement with theory. Reduction of each of the tetramers provides c s-l,2-c s-4,5-tetrakis(5-tocopheryl)cyclohexane (45). The dashed lines separate the two former units of 43, indicating where bond formation during the spiro oligomerization process occurred. 

The bi- and tridentate phosphines dppp (l,3-bis(diphenylphosphino)propane) and dppep (bis (2-diphenylphosphinoethyl)phenylphosphine) have been complexed with Co and their divalent four- and five-coordinated thiophenolate complexes Co(dppp)(SPh)2 and Co(dppep)(SPh)2 have been isolated and structurally characterized.379 Somewhat related to dppp is the bidentate silane Ph2PCH2SiMe2CH2PPh2, which forms high-spin, pseudo-tetrahedral dihalocobalt(II) complexes.380... 

The novel tetrabasic ligand l,3-bis(5-methylpyrazole-3-carboxamido)propane forms a trinuc-lear Co111 Co11 Co111 complex (196). The tetradentate diamide-pyrazolyl chelates encircle the terminal trivalent metal ions while the central divalent Co is in a distorted tetrahedral environment provided by the four bridging pyrazolyl rings.881... 

Figure 54 Product of the reaction of l,3-bis(diphenylphosphino)propane (dppp) palladium(II) complex with...

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