Propane-1,2-diamine

Benzaldehyde monohydrazone, 2,3-butanedione monohydrazone and related hydrazones have been found to react with some ketones in the presence of nickel(II), affording compounds which, in turn, condense with either en or propane-1,2-diamine giving macrocyclic complexes (Scheme 49).2656 2657... 

The application of 59Co n.m.r. spectroscopy to the study of cobalt(m) complexes is beginning to expand.285,286 An n.m.r. study of the stereoisomers of propane-1,2-diamine (pn), en, acac, CF3acac, etc., showed that the chemical shifts do not appear to be related to the absolute configuration, but that larger linewidths are observed with lower symmetry complexes 286 The chemical shifts are larger for ob-lel than for mer-fac isomerism in Co(pn)3 +. 285... 

Mono-aqua adducts of dimethyltin dichloride with [NinL] H2O [H2L = N,N -bis (3-methoxysalicylidene)ethylenediamine] and iV,iV,-bis(3-methoxysalicylidene)propane-1,2-diamine] have different structures. In the former the tin is in a TBP environment, whereas in the latter it is in an octahedral environment as a result of an intermolecular Cl Sn contact of 3.615 A426. 

The application of molecular mechanics to metal complexes developed in parallel with its application to organic molecules. Indeed, the earliest report that considered the importance of nonbonded interactions in determining the relative stabilities of isomeric molecules was a 1944 study of the six isomers of the coordination compound [Co((5)-pn)2(N02)2] (pn = propane-1,2-diamine)[1]. A number of similar, though more detailed, studies in the 1950s and 1960s l-2 4] led to the full application of molecular mechanics to metal complexes. The common theme... 

A hydroformylation-cyclocondensation of iV-alkenylpropane-1,3-diamines, such as 159 (prepared by reductive amination of the appropriate unsaturated aldehyde with either propane-1,2-diamine or 2-aminoethanol and subsequent borohydride reduction), in the presence of PPh3 and BIPHENPHOS as ligand provided different reaction products depending on the H2/CO ratio <1999AJC1131>. The bicyclic system 160 was accompanied by 10% branched 162 when H2/CO was 1 1 (Scheme 66). Reaction with H2/CO in a 1 5 ratio provided solely the bicyclic system, while only a mixture of monoalcohols 161 and 162 was isolated when the reaction was performed in the absence of PPh3. 

Asn = asparagine CitH2 = citric acid tu = thiourea see Thiourea), Ettu = ethylenethiourea Glu = glutamic acid Met = methionine tren = tris(2-aminoethyl)amine Mee tren = tris(2-dimethylaminoethyl)amine, en = ethane-1,2-diamine pn = propane-1,2-diamine. 

Co = Catechol oxidase He = Hemocyanin Tyr = Tyrosinase MePy2 = Al,Al-bis(2-pyridylethyl)methylamine TACN = l,3,5-triazocyclononane TMPA = Tris[(2-pyridyl) methyljamine XYL-O = Q ,Q -bis[Al,Al-bis(2-pyridylethyl) amino]-m-xylene-2-olate XYL = Q ,Q -bis[A, Al-bis(2-pyri-dylethyl)amino]-m-xylene XYL-R = Meta substituted a,a -bis[Al,Al-bis(2-pyridylethyl)amtno]-m-xylene N3 = N,N, Al -Tetrakis-(2-pyridin-2-yl-ethyl)-propane-1,2-diamine N4 = Al,Al,Al, Al -Tetrakis-(2-pyridin-2-yl-ethyl)-butane-1,2-diamine N5 = Al,Al,Al, Al -Tetrakis-(2-pyridin-2-yl-... 

Repeat the procedure outlined above to calculate the energy profile and energy barrier associated with the conformational interconversion in [Co(NH3)4(propane-1,2-diamine)], built and minimized in Sections 17.4 and 17.5, respectively. Compare the results you obtain with those for [Co(NH3)4(en)] " ". 

Fig, 5.2, CD spectra of the tetrafluoroborate salt of the frans-bis (ii-propane-1,2-diamine) dichlorocobaltate(Ill) complex, determined in solutions prepared with various non-aqueous solvents [Ha 77]... 

The formation of macrocyclic species decreases dramatically on going from ethane-1,2-diamine to propane-1,2-diamine and further to 2-methylpropane-1,2-diamine. 

Analogously, bis(i -l,2-diaminopropane)nickel(II) perchlorate reacts with acetone to give the RR-[Ni(L211)2] isomer, which is converted in pyridine exclusively into the / R-[Ni(L212)] + isomer [251]. Reaction of tris(propane-1,2-diamine) nickel(II) perchlorate prepared from racemic diamine with acetone affords C-rac and C-meso isomers of [Ni(L212)] + in approximately equal amounts [218, 251]. 

The tris( propane-1,2-diamine)copper( II) perchlorate containing racemic diamine reacts with acetone to yield a mixture of two species - [Cu(L212)](C104)2 in its meso form and, presumably, the C-rac isomer [251]. 

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