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Promotion stage of carcinogenesis

The tumor-promoting activity of OA can be also partially related to other actions at cellular level, such as oxidation of different substrates, methylation of DNA bases, and inhibitory mechanisms of gap intracellular communication, which is believed to be of importance in the promotion stage of carcinogenesis. An additional factor hypothesized to contribute to the tumor promotion by OA is amplification of genes conferring multidrug resistance to cells. ... [Pg.238]

Figure 9.5 Karyotypic changes during initiation, promotion, and progression stages of carcinogenesis. Figure 9.5 Karyotypic changes during initiation, promotion, and progression stages of carcinogenesis.
In contrast, promotion is reversible to some extent, and it is only effective following, not preceding, the initiating events. These discoveries suggest that only the initiation stage of carcinogenesis has an absolute requirement for the chemical carcinogen. [Pg.11]

The stage of carcinogenesis at which the effect of dietary fat is exerted appears to be during the promotional phase of carcino-... [Pg.128]

Murakoshi, M. et al.. Potent preventive action of a-carotene against carcinogenesis spontaneous liver carcinogenesis and promoting stage of lung and skin carcinogenesis in mice are suppressed more effectively by a-carotene than by P-carotene, Cancer Res., 52, 6583, 1992. [Pg.176]

Inano, H., Onoda, M., Inafuku, N., Kubota, M., Kamada, Y., Osawa, T., Kobayashi, H., and Wakabayashi, K., Chemoprevention by curcumin during the promotion stage of tumorigenesis of mammary gland in rats irradiated with gamma-rays. Carcinogenesis, 20, 1011, 1999. [Pg.191]

See other pages where Promotion stage of carcinogenesis is mentioned: [Pg.929]    [Pg.930]    [Pg.282]    [Pg.32]    [Pg.128]    [Pg.169]    [Pg.327]    [Pg.269]    [Pg.209]    [Pg.432]    [Pg.211]    [Pg.56]    [Pg.705]    [Pg.194]    [Pg.174]    [Pg.118]    [Pg.131]    [Pg.131]    [Pg.134]    [Pg.929]    [Pg.930]    [Pg.282]    [Pg.32]    [Pg.128]    [Pg.169]    [Pg.327]    [Pg.269]    [Pg.209]    [Pg.432]    [Pg.211]    [Pg.56]    [Pg.705]    [Pg.194]    [Pg.174]    [Pg.118]    [Pg.131]    [Pg.131]    [Pg.134]    [Pg.310]    [Pg.203]    [Pg.181]    [Pg.181]    [Pg.182]    [Pg.12]    [Pg.75]    [Pg.104]    [Pg.33]    [Pg.246]    [Pg.332]    [Pg.35]    [Pg.329]    [Pg.127]    [Pg.175]    [Pg.134]    [Pg.310]    [Pg.310]    [Pg.4821]    [Pg.327]    [Pg.90]    [Pg.256]    [Pg.117]    [Pg.209]   
See also in sourсe #XX -- [ Pg.174 ]



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