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Proloprim - Trimethoprim

Proiifen - Ciomiphene dihydrogen citrate Prolix Apazone Prolixan - Apazone Prolixano - Apazone Prolixin Fluphenazine HCI Prolopa Benserazide Proloprim - Trimethoprim Promachlor - Chlorpromazine HCI Promacid - Chlorpromazine HCI Promactii - Chlorpromazine HCI Promanyi - Promazine HCI Promapar Chlorpromazine HCI Promassolax - Oxyphenisatin acetate... [Pg.1733]

Trimethoprim (Trimpex, Proloprim) is a structural analogue of the pteridine portion of dihydrofolic acid. It differs from the sulfonamides in that it acts at a second step in the folic acid synthetic pathway that is, it... [Pg.517]

Pyrimethamine (Daraprim) is the best of a number of 2,4-diaminopyrimidines that were synthesized as potential antimalarial and antibacterial compounds. Trimethoprim (Proloprim) is a closely related compound. [Pg.614]

Trimethoprim (Proloprim, Trimpex) interferes with the bacterial folic acid pathway by inhibiting the dihydrofolate reductase enzyme in susceptible bacteria (see Fig. 33-2). This enzyme converts dihydrofolic acid to tetrahydrofolic acid during the biosynthesis of folic acid cofactors. By inhibiting this enzyme, trimethoprim directly interferes with the production of folic acid cofactors, and subsequent production of vital bacterial nucleic acids is impaired. [Pg.513]

The introduction of trimethoprim in combination with sulfamethoxazole constitutes an important advance in the development of clinically effective antimicrobial agents. In addition to its combination with sulfamethoxazole (bactrim, septra, others), trimethoprim also is available as a singleentity preparation (proloprim, others). It is a diaminopyramidine. [Pg.720]

Trimethoprim (Proloprim) Not a sulfonamide. Inhibits dihydrofolate reductase, the enzyme which reduces tetrahydrofolate (Fig. 7.14). Enteric Gram-negatives (Proteus, E. coti, Klebsiella, Enterobacter), H influenzae, Shiigella, Serratia, Salmonella, Pneumocystis carinii Urinary tract infections, acute otitis media in children. [Pg.110]

Trimethoprim Triprim Proloprim Monotrim Dihydrofolate reductase inhibitor Treatment of urinary tract infections. NH2... [Pg.1330]

See other pages where Proloprim - Trimethoprim is mentioned: [Pg.1733]    [Pg.363]    [Pg.364]    [Pg.1177]    [Pg.1391]    [Pg.1345]    [Pg.1389]    [Pg.1733]    [Pg.363]    [Pg.364]    [Pg.1177]    [Pg.1391]    [Pg.1345]    [Pg.1389]    [Pg.349]    [Pg.57]    [Pg.313]    [Pg.1040]    [Pg.56]    [Pg.313]    [Pg.510]    [Pg.1087]    [Pg.93]    [Pg.133]    [Pg.283]    [Pg.709]    [Pg.647]    [Pg.56]    [Pg.313]    [Pg.591]   


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Proloprim

Trimethoprim

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