Progress in MIP Technology

There are number of potential application areas that have been identified for MIPs all based on their capability to specifically recognize molecular targets affinity separation (Wei and Mizaikoff, 2007), chemical sensors and assays (Qiu et al., 2012 Tokonami et al.. 

directed synthesis and enzyme-like catalysis (Chai et al., 2012), and biomedical applications [Yanez et al., 2011). 

As MIPS made gradual transition from the academic research laboratory to pharmaceutical application areas, it became essential that the MIPs are designed, both chemically and structurally, in order to optimize its performance for these application. There have been several attempts on the development of generic procedure for MIPs such as combinatorial synthesis/ screening (Batra and Shea, 2003) and Chemometrics (Gholivand et al., 2012) however, the in silico-based computational design has been in prime focus in the past decade. 

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