Preterm infants gastric

Because of the premature infent s small body mass and less mature cardiovascular and cerebrovascular status, prudence dictates using the lowest concentration yet the most effective combination of mydriatics for pupillary dilation. A combination of 2.5% phenylephrine and 0.5% to 1.0% tropicamide provides sufficient mydriasis without adverse cardiovascular effects in preterm infents.The use of tropicamide alone, however, does not generally produce a sufficient mydriasis in premature infants. Adding cyclopentolate to the tropicamide regimen improves mydriasis but may contribute to elevated blood pressure and heart rate. Moreover, because of possible gastric secretory inhibition in preterm infants, the concentration of cyclopentolate should be limited to 0.25%. A commercially available combination of 1% phenylephrine and... 

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G. Effect of a prebiotic mixture of short chain galacto-ohgosaccharides and long chain fructo-on gastric motility in preterm infants. J Pediatr Gastroenterol Nutr 2007 44(Suppl l) e217. 

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